UniProt archive

UniProt archive
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DOI:
10.1093/bioinformatics/bth191
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发表时间:
2004-11-22
期刊:
影响因子:
5.8
通讯作者:
Apweiler, R
Apweiler, R
中科院分区:
生物学3区
文献类型:
--
作者:
Leinonen, R;Diez, FG;Apweiler, R

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UniProt Archive (UniParc)是最全面、无冗余的蛋白质序列数据库。它的蛋白质序列是从主要的,公开可访问的资源检索。所有新的和更新的蛋白质序列收集和加载到UniParc每天为全面覆盖。为了避免冗余,每个唯一序列仅存储一次,并使用稳定的蛋白质标识符,这可以在UniParc中稍后使用,以识别所有源数据库中的相同蛋白质。当蛋白质被加载到数据库中时,就会创建数据库交叉引用,将它们与序列的起源联系起来。因此,对UniParc执行序列搜索相当于对UniParc交叉引用的所有数据库执行相同的搜索。UniParc只包含蛋白质序列和数据库交叉引用;所有其他信息都必须从源数据库中检索。
UniProt Archive (UniParc) is the most comprehensive, non-redundant protein sequence database available. Its protein sequences are retrieved from predominant, publicly accessible resources. All new and updated protein sequences are collected and loaded daily into UniParc for full coverage. To avoid redundancy, each unique sequence is stored only once with a stable protein identifier, which can be used later in UniParc to identify the same protein in all source databases. When proteins are loaded into the database, database cross-references are created to link them to the origins of the sequences. As a result, performing a sequence search against UniParc is equivalent to performing the same search against all databases cross-referenced by UniParc. UniParc contains only protein sequences and database cross-references; all other information must be retrieved from the source databases.