Development of bilateral coronary artery aneurysms in a child with Noonan syndrome
Development of bilateral coronary artery aneurysms in a child with Noonan syndrome
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DOI：
10.1007/s00247-015-3472-z
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发表时间：
2016-03-01
影响因子：
2.3
通讯作者：
Hagspiel, Klaus D.
中科院分区：
文献类型：
--
作者：
Mauro, David M.;Flors, Lucia;Hagspiel, Klaus D.
努南综合征是一系列先天性畸形，包括心脏缺陷、面部畸形和身材矮小。心血管缺陷多种多样，范围广泛，最常见的是肺动脉瓣狭窄和肥厚型心肌病。冠状动脉异常仅在少数病例中被报道。我们报告一位患努南综合症的儿童，在接受肺动脉狭窄及房间隔缺损修补术后，发展为双侧冠状动脉动脉瘤。通过心脏磁共振成像和冠状动脉CT血管成像诊断了这些动脉瘤。在5年前的心脏磁共振检查中，没有他们的证据。
Noonan syndrome is a constellation of congenital malformations including heart defects, facial anomalies and short stature. The cardiovascular defects are variable and extensive, with the most common being pulmonary stenosis and hypertrophic cardiomyopathy. Coronary artery anomalies have only been reported in a few cases. We report a child with Noonan syndrome status post pulmonary stenosis and atrial septal defect repair, who developed bilateral coronary artery aneurysms. The aneurysms were diagnosed with both cardiac magnetic resonance imaging and coronary computed tomography angiography. There had been no evidence of them on a cardiac MR exam 5 years previously.