Musculoskeletal model-guided, customizable selection of shoulder and elbow muscles for a C5SCI neuroprosthesis
Musculoskeletal model-guided, customizable selection of shoulder and elbow muscles for a C5SCI neuroprosthesis
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DOI：
10.1109/tnsre.2008.922681
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发表时间：
2008-06-01
影响因子：
4.9
通讯作者：
Kirsch, Robert F.
中科院分区：
文献类型：
--
作者：
Hincapie, Juan Gabriel;Blana, Dimitra;Kirsch, Robert F.
C5/C6脊髓损伤（SCI）患者的上肢有许多瘫痪的肌肉，可以进行电击。以协调的方式激活以恢复功能。选择一个实际的子集麻痹肌肉刺激取决于个人的具体条件，功能恢复的目标，和手术的考虑。本文提出了一种基于肌肉骨骼模型的方法，用于优化肌肉设置功能性电刺激（FES）的肩膀和肘部在这个人群中。实验记录的运动学健全的受试者作为输入到肌肉骨骼模型的肩膀和肘部，这是修改，以反映与C5 SCI的个人的肌肉力量能力降低，但也有潜力使用FES激活瘫痪的肌肉。进行了大量模拟典型日常生活活动的逆动态模拟，包括1）保留自主控制的肌肉和2）刺激麻痹肌肉的许多不同组合。这些结果表明，由前锯肌、冈下肌和三头肌组成的肌肉组将能够实现最大范围的相关运动。该套件将成为C5 SCI神经假体的初始目标，以恢复肩关节和肘关节功能。
Individuals with C5/C6 spinal cord injury (SCI) have a number of paralyzed muscles in their upper extremities that can be electrically. activated in a coordinated manner to restore function. The selection of a practical subset of paralyzed muscles for stimulation depends on the specific condition of the individual, the functions targeted for restoration, and surgical considerations. This paper presents a musculoskeletal model-based approach for optimizing the muscle set used for functional electrical stimulation (FES) of the shoulder and elbow in this population. Experimentally recorded kinematics from able-bodied subjects served as inputs to a musculoskeletal model of the shoulder and elbow, which was modified to reflect the reduced muscle force capacities of an individual with C5 SCI but also the potential of using FES to activate paralyzed muscles. A large number of inverse dynamic simulations mimicking typical activities of daily living were performed that included 1) muscles with retained voluntary control and 2) many different combinations of stimulated paralyzed muscles. These results indicate that a muscle set consisting of the serratus anterior, infraspinatus and triceps would enable the greatest range of relevant movements. This set will become the initial target in a C5 SCI neuroprosthesis to restore shoulder and elbow function.