The capillary blood pressure in mammalian mesentery as determined by the micro-injection method
The capillary blood pressure in mammalian mesentery as determined by the micro-injection method
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DOI：
10.1152/ajplegacy.1930.93.1.353
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发表时间：
1930-05-01
影响因子：
--
通讯作者：
Landis, EM
中科院分区：
文献类型：
--
作者：
Landis, EM
本文用微量注射法测定毛细血管血压，研究了去大脑大鼠和麻醉豚鼠肠系膜血管的压力降。这种方法允许测量平均压力，而不会干扰所观察的血管中的流动。毛细血管血压范围为22至49厘米。2/3的测定值位于25至35 cm之间。微动脉毛细血管平均压力为30 cm。在大鼠和38.5厘米。在豚鼠中，而在静脉毛细血管中，平均血压为17 cm。两个都是血压的下降并不是在微动脉和毛细血管的交界处突然停止，而是继续到静脉毛细血管。大鼠、豚鼠和青蛙的压力梯度显示了小动脉和毛细血管之间的外周阻力的类似划分。在大鼠、豚鼠和青蛙中观察到平均毛细血管血压和血浆蛋白渗透压之间的平衡。然而，哺乳动物与青蛙的不同之处在于维持这种平衡的更高水平的压力。平均小动脉毛细血管压高于血浆蛋白的渗透压，平均静脉毛细血管压低于血浆蛋白的渗透压。这些发现为支持哺乳动物液体交换的Starling假说提供了证据。
The micro-injection method for determination of blood pressure in individual capillaries was used in studying pressure fall in the mesenteric vessels of decerebrate rats and anesthetized guinea pigs. This method permitted the measurement of mean pressure, without disturbance of flow in the observed vessel. Capillary blood pressures ranged from 22 to 49 cm. of water with 2/3 of the determinations lying between 25 to 35 cm. Average pressure in the arteriolar capillary was 30 cm. in the rat and 38.5 cm. in the guinea pig, while in the venous capillary the average blood pressure was 17 cm. in both. The fall of blood pressure did not cease abruptly at the junction of the arteriole and capillary, but continued to the venous capillary. The pressure gradients of the rat, guinea pig and frog showed a similar division of peripheral resistance between the arterioles and capillaries. A balance between average capillary blood pressure and the osmotic pressure of the plasma proteins has been observed in the rat, guinea pig and frog. The mammals, however, differ from the frog in the higher level of pressure at which this balance is maintained. Average arteriolar capillary blood pressure was above, and average venous capillary pressure was below, the osmotic pressure of the plasma proteins. The findings provide evidence in favor of the Starling hypothesis of fluid interchange in mammals.