Gene Unscrambler for detangling scrambled genes in ciliates

Gene Unscrambler for detangling scrambled genes in ciliates
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DOI:
10.1093/bioinformatics/bth003
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发表时间:
2004-03-22
期刊:
影响因子:
5.8
通讯作者:
Landweber, LF
Landweber, LF
中科院分区:
生物学3区
文献类型:
--
作者:
Cavalcanti, ARO;Landweber, LF

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总结:混乱的基因在某些种类的纤毛虫中惊人地普遍。到目前为止,还没有软件可以自动分析这些基因。我们在这里提出了一个程序,可以自动对齐的大核和微核形式的基因,输出的大核的目的片段和指针序列的位置。
Summary: Scrambled genes are surprisingly common in some species of ciliates. Until now there was no software available to analyze automatically these genes. We present here a program that can automatically align the macronuclear and micronuclear forms of a gene, outputting the location of the macronuclear destined segments and pointer sequences.