Responses of neurons in the rat's ventral nucleus of the lateral lemniscus to monaural and binaural tone bursts.
Responses of neurons in the rat's ventral nucleus of the lateral lemniscus to monaural and binaural tone bursts.
复制标题
大鼠外侧丘系腹核神经元对单耳和双耳音爆发的反应。
DOI：
10.1152/jn.01215.2005
复制
发表时间：
2006
影响因子：
2.5
通讯作者：
J. Kelly
中科院分区：
文献类型：
--
作者：
Huiming Zhang;J. Kelly
记录大鼠外侧丘系腹核 (VNLL) 神经元对单耳和双耳突发音的反应。大多数神经元 (55%) 具有 V 形或 U 形频率调谐曲线，具有单一明确定义的特征频率 (CF)。然而，许多神经元具有更复杂的多峰调谐曲线（37%）或其他模式（8%）。颞发射模式包括对对侧突发音调的起始反应和持续反应。起始反应和持续反应沿着 VNLL 的背腹长度分布，没有迹象表明存在不同区域的分离。起始神经元的平均首次尖峰潜伏期比持续反应的神经元要短（平均值分别为 8.3 毫秒和 14.8 毫秒）。与具有持续响应的神经元相比，它们的抖动也更小，这反映在第一个尖峰延迟的 SD 中（平均值分别为 0.59 和 4.2 毫秒）。对于具有持续反应的神经元，抖动程度随着刺激强度的增加而减小，但对于在相同范围内测试的起始神经元来说，抖动程度保持不变。许多神经元具有双耳反应，主要是兴奋/抑制（EI）类型，广泛分布于 VNLL 的背腹侧范围。 AMPA 受体拮抗剂 NBQX 的局部应用减少了兴奋反应，表明反应依赖于突触活动，而不是从通过的纤维记录的。结果表明，VNLL 中的许多神经元具有非常适合处理听觉时间信息的计时精度。在大鼠中，这些神经元混合在时间响应特征不太精确的细胞中，包括具有双耳和单耳响应的细胞。
Responses to monaural and binaural tone bursts were recorded from neurons in the rat's ventral nucleus of the lateral lemniscus (VNLL). Most of the neurons (55%) had V- or U-shaped frequency-tuning curves with a single clearly defined characteristic frequency (CF). However, many neurons had more complex, multipeaked tuning curves (37%), or other patterns (8%). Temporal firing patterns included both onset and sustained responses to contralateral tone bursts. Onset and sustained responses were distributed along the dorsoventral length of VNLL with no indication of segregation into different regions. Onset neurons had shorter average first-spike latencies than neurons with sustained responses (means, 8.3 vs. 14.8 ms). They also had less jitter, as reflected in the SD of first-spike latencies, than neurons with sustained responses (means, 0.59 and 4.2 ms, respectively). The extent of jitter decreased with an increase in stimulus intensity for neurons with sustained responses, but remained unchanged for onset neurons tested over the same range. Many neurons had binaural responses, primarily of the excitatory/inhibitory (EI) type, widely distributed along the dorsoventral extent of VNLL. Local application of the AMPA receptor antagonist NBQX reduced excitatory responses, indicating that responses were dependent on synaptic activity and not recorded from passing fibers. The results show that many neurons in VNLL have a precision of timing that is well suited for processing auditory temporal information. In the rat, these neurons are intermingled among cells with less precise temporal response features and include cells with binaural as well as monaural responses.
对外侧丘系腹侧核内侧部分的耳间时间差异敏感的神经元。
DOI：
10.1152/jn.1997.78.1.511
发表时间：
1997
期刊：
Journal of neurophysiology.
影响因子：
--
作者：
Batra,R;Fitzpatrick,DC
通讯作者：
Fitzpatrick,DC
影响因子：
2.5
作者：
COVEY, E
通讯作者：
COVEY, E
γ-氨基丁酸和甘氨酸免疫反应性的模式反映了猫外侧丘系核的结构和功能差异。
DOI：
10.1002/(sici)1096-9861(19971215)389:2
发表时间：
1997
期刊：
The Journal of comparative neurology
影响因子：
--
作者：
SaintMarie,RL;Shneiderman,A;Stanforth,DA
通讯作者：
Stanforth,DA