Utility loss and indirect costs following cardiovascular events in hypertensive patients:: the ASCOT health economic substudy
Utility loss and indirect costs following cardiovascular events in hypertensive patients:: the ASCOT health economic substudy
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DOI：
10.1007/s10198-006-0002-9
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发表时间：
2007-03-01
影响因子：
4.4
通讯作者：
Jonsson, Bengt
中科院分区：
文献类型：
--
作者：
Lindgren, Peter;Kahan, Thomas;Jonsson, Bengt
这项研究评估了与首次心血管事件相关的效用损失和间接成本。在盎格鲁-斯堪的纳维亚心脏结果试验 (ASCOT) 瑞典部分的事件发生后 3、6 和 12 个月前瞻性收集数据（使用 EQ-5D），包括患有轻度至中度高血压和其他危险因素的患者。六十名患者有资格进行分析。事件与一年公用事业损失 0.075 相关（95% CI：0.038-0.114）。对于中风，降低为 0.1.45（CI：0.059-0.249），对于急性冠状动脉综合征（心肌梗塞或不稳定心绞痛），降低为 0.051（-0.003 至 0.103）。基线的效用与对照组的效用没有什么不同。前 12 个月的间接成本（2003 瑞典克朗，SEK）为 90028 SEK（CI：46027-146754），劳动力患者为 9866 EK。这些结果有助于未来心血管医学一级预防措施的经济评估。
This study assessed the loss of utility and indirect costs associated with first cardiovascular events. Data was collected (using EQ-5D) prospectively at 3, 6, and 12 months following an event in the Swedish part of the Anglo-Scandinavian cardiac outcomes trial (ASCOT), including patients with mild to moderate hypertension and additional risk factors. Sixty patients were eligible for analysis. An event was associated with a one-year utility loss of 0.075 (95% CI: 0.038-0.114). For a stroke, the reduction was 0.1.45 (CI: 0.059-0.249) and for acute coronary syndromes (myocardial infarction or unstable angina) the loss was 0.051 (-0.003 to 0.103). The utility at baseline was no different to the utility in a control group. The indirect cost over the first 12 months (2003 Swedish Kronor, SEK) was 90028 SEK (CI: 46027-146754), 9866 E for patients in the workforce. These results are helpful in future economic evaluations of primary preventive measures in cardiovascular medicine.