Neonatal Abstinence Syndrome: Treatment and Pediatric Outcomes

Neonatal Abstinence Syndrome: Treatment and Pediatric Outcomes
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DOI:
10.1097/grf.0b013e31827feea4
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发表时间:
2013-03-01
影响因子:
1.5
通讯作者:
Hayes, Marie J.
Hayes, Marie J.
中科院分区:
医学4区
文献类型:
--
作者:
Logan, Beth A.;Brown, Mark S.;Hayes, Marie J.

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最近孕妇中阿片替代疗法的比率上升,导致需要治疗新生儿戒断综合征的婴儿人数增加。与产前阿片类药物暴露相关的短期和长期发育结果进行了讨论,包括NAS的症状和严重程度,以及早期认知和运动延迟。产妇和婴儿的风险因素进行了讨论,并包括模式的母亲在怀孕期间使用的物质,遗传风险,多物质暴露药理治疗NAS和母乳喂养。表征的重要性,必然的环境风险因素也被认为是。
Recent rise in rates of opiate replacement therapy among pregnant women have resulted in increasing number of infants requiring treatment for neonatal abstinence syndrome (NAS). Short-term and long-term developmental outcomes associated with prenatal opiate exposure are discussed, including symptoms and severity of NAS, and early cognitive and motor delays. Maternal and infant risk factors are discussed, and include patterns of maternal substance use during pregnancy, genetic risk, polysubstance exposure pharmacological treatment for NAS and breastfeeding. The importance of characterizing corollary environmental risk factors is also considered.