HYPER-CALCEMIA IN ACTIVE PULMONARY TUBERCULOSIS
HYPER-CALCEMIA IN ACTIVE PULMONARY TUBERCULOSIS
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DOI：
10.7326/0003-4819-90-3-324
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发表时间：
1979-01-01
影响因子：
39.2
通讯作者：
ARNSTEIN, AR
中科院分区：
文献类型：
--
作者：
ABBASI, AA;CHEMPLAVIL, JK;ARNSTEIN, AR
测定了79名连续活动性肺结核患者和79名慢性阻塞性肺病患者的对照组的高钙血症发生率。患者（22例）在结核病化疗开始后4 - 16周发生高钙血症（血清Ca> 10.5 mg/dl）。高钙血症持续时间1-7个月。所有患者均自发缓解。高钙血症患者的平均每日维生素D补充量高于正常钙血症组。每日补充维生素D与高钙血症的程度和持续时间呈正相关。肺结核患者的平均血清钙高于补充相同剂量维生素D的慢性阻塞性肺疾病患者。高钙血症可能与肺结核的活动性及维生素D的摄入有关。
The incidence of hypercalcemia was determined in 79 consecutive patients with active pulmonary tuberculosis and a control group of 79 patients with chronic obstructive pulmonary disease. Patients (22) developed hypercalcemia (serum Ca greater than 10.5 mg/dl) 4-16 wk after initiation of chemotherapy for tuberculosis. The duration of hypercalcemia ranged from 1-7 mo. and remission occurred spontaneously in all patients. The mean daily vitamin D supplement was greater in hypercalcemic patients than in the normocalcemic group. There was a positive correlation between daily vitamin D supplement and degree and duration of hypercalcemia. Mean serum Ca in patients with tuberculosis was higher than in patients with chronic obstructive pulmonary disease supplemented with the same dose of vitamin D. Hypercalcemia may be related to the activity of pulmonary tuberculosis and the intake of vitamin D.