Inhibition of Helicobacter pylori adhesion to human gastric mucus by a high-molecular-weight constituent of cranberry juice
Inhibition of Helicobacter pylori adhesion to human gastric mucus by a high-molecular-weight constituent of cranberry juice
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DOI：
10.1080/10408390209351916
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发表时间：
2002-01-01
影响因子：
10.2
通讯作者：
Ofek, I
中科院分区：
文献类型：
--
作者：
Burger, O;Weiss, E;Ofek, I
已经发现，小红莓汁的一种高分子成分可以抑制幽门螺杆菌菌株与固定化的人粘液、红细胞和培养的胃上皮细胞的唾液乳糖特异性黏附。不同的幽门螺杆菌菌株对酸莓汁成分的亲和力不同。小红莓汁还可以在体内抑制细菌与胃的黏附，并可能被证明对预防幽门螺杆菌引起的胃溃疡有用。
A high-molecular-weight constituent of cranberry juice has been found to inhibit the sialyllactose specific adhesion of Helicobacter pylori strains to immobilized human mucus, erythrocytes, and cultured gastric epithelial cells. Different isolates of H. pylori differ in their affinity to the cranberry juice constituent. Cranberry juice may also inhibit adhesion of bacteria to the stomach in vivo, and may prove useful for the prevention of stomach ulcer that is caused by H. pylori.