Light treatment for sleep disorders: Consensus report .7. Jet lag

Light treatment for sleep disorders: Consensus report .7. Jet lag
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DOI:
10.1177/074873049501000209
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发表时间:
1995-06-01
影响因子:
3.5
通讯作者:
Eastman, CI
Eastman, CI
中科院分区:
生物学3区
文献类型:
--
作者:
Boulos, Z;Campbell, SS;Eastman, CI

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睡眠障碍是一种再熟悉不过的时差反应症状,也是跨子午线旅行者和机组人员抱怨的主要原因。它们是突然改变的睡眠周期(根据新的当地昼夜周期计时)和逐渐重新引入的昼夜节律系统之间暂时失去同步的结果。原则上,有计划地暴露在明亮的光线下可以通过加速生物钟重新进入新的时区来减轻时差症状。实验室模拟,其中睡眠时间提前6至8小时,受试者在连续2至4天的主观夜间暴露于强光3至4小时,并没有全部成功。迄今为止进行的几项实地研究取得了令人鼓舞的结果,但由于样本量非常有限,这些研究是否适用于广大人口仍不确定。尚未解决的问题包括第一天以及随后治疗日的最佳曝光时间,给定的固定曝光时间是否可能使大多数旅行者受益,或者是否应该根据某些个人昼夜节律相位标记来安排光治疗,如果是这样,可以找到这样的相位标记既实用又可靠。
Sleep disturbances are an all-too-familiar symptom of jet lag and a prime source of complaints for transmeridian travelers and flight crews alike. They are the result of a temporary loss of synchrony between an abruptly shifted sleep period, timed in accordance with the new local day-night cycle, and a gradually reentraining circadian system. Scheduled exposure to bright light can, in principle, alleviate the symptoms of jet lag by accelerating circadian reentrainment to new time zones. Laboratory simulations, in which sleep time is advanced by 6 to 8 h and the subjects exposed to bright light for 3 to 4 h during late subjective night on 2 to 4 successive days, have not all been successful. The few field studies conducted to date have had encouraging results, but their applicability to the population at large remains uncertain due to very limited sample sizes. Unresolved issues include optimal times for light exposure on the first as well as on subsequent treatment days, whether a given, fixed, light exposure time is likely to benefit a majority of travelers or whether Light treatment should be scheduled instead according to some individual circadian phase marker, and if so, can such a phase marker be found that is both practical and reliable.