Ubiquitination, proteasomes and GABAA receptors
Ubiquitination, proteasomes and GABAA receptors
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DOI:
10.1038/ncb1001-e232
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发表时间:
2001-10-01
影响因子:
21.3
通讯作者:
Keller, CA
中科院分区:
文献类型:
--
作者:
Lüscher, B;Keller, CA
Inhibitory neurotransmission by gamma -aminobutyric acid (GABA) is regulated by the number and subcellular localization of GABA(A) receptors in the membrane of the target neuron. A new study suggests that the ubiquitin-like protein Plic-1 stabilizes intracellular GABA(A) receptors and promotes their accumulation in the plasma membrane.