Antidiabetic potential of Phyllanthus reticulatus in alloxan-induced diabetic mice
Antidiabetic potential of Phyllanthus reticulatus in alloxan-induced diabetic mice
复制标题
DOI：
10.1016/j.fitote.2007.06.012
复制
发表时间：
2008-01-01
期刊：
影响因子：
3.4
通讯作者：
Rangari, V. D.
中科院分区：
文献类型：
--
作者：
Kumar, S.;Kumar, D.;Rangari, V. D.
植物叶下珠被声称在部落地区具有抗糖尿病活性。为了验证部落的声明，在四氧嘧啶诱导的糖尿病小鼠中口服500和1000 mg/kg的网纹草叶的石油醚和乙醇提取物的降血糖作用。其在1000 mg/kg剂量下显示出抗糖尿病活性。残留物的植物化学筛选揭示了萜类化合物糖苷，蛋白质，碳水化合物的存在和生物碱和类固醇的情况下。(c)2007 Elsevier B. V.保留所有权利。
The plant Phyllanthus reticulatus is claimed to have antidiabetic activity in tribal area. To validate the tribal claim, the petroleum ether and ethanolic extracts of leaves of the P reticulatus were orally tested at 500 and 1000 mg/kg for hypoglycemic effect in alloxan induces diabetic mice. It shows antidiabetic activity at the dose of 1000 mg/kg. The phytochemical screening of the residues revealed the presence of terpenoids glycosides, protein, carbohydrates and absence of alkaloids and steroids. (c) 2007 Elsevier B.V. All rights reserved.