Combustion synthesis of porous biomaterials
Combustion synthesis of porous biomaterials
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DOI：
10.1002/jbm.a.31017
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发表时间：
2007-06-01
影响因子：
4.9
通讯作者：
Moore, John J.
中科院分区：
文献类型：
--
作者：
Ayers, Reed A.;Burkes, Douglas E.;Moore, John J.
本文讨论了自传播高温合成（SHS）独特的材料制造工艺，并将其应用于多孔生物材料的制备。多孔材料一直被认为是实现体内骨组织工程和制造患者终身植入物的第一步。作者通过利用燃烧合成来应对这一挑战，创造了新型材料，如NiTi + TiC，以及通常被生物医学应用所接受的多孔材料，如磷酸三钙和羟基磷灰石。在SHS产品中，物理化学性质由但不限于反应物化学计量学控制；生坯密度;混合反应物的粒度；气化剂的使用或存在；反应物的升温速率和重力。通过平衡这些参数，可以控制反应的能量，以产生所需的产物化学计量、孔隙率和机械性能。SHS提供了一种快速制造材料的方法，节省了时间和生产成本，并通过使用单个模具实现了定制设备的合成。模具材料可以从石墨到纸或纸刀。燃烧合成提供了一种快速制造负担得起的个体生物医学设备的方法，这将减少患者的恢复时间。(C) 2006 Wiley期刊有限公司[J] .中国生物医学工程学报，2016,31(2):444 - 444。
This article discusses the unique material manufacturing process of self-propagating high temperature synthesis (SHS) as applied to the making of porous biomaterials. Porous materials have long been considered as the first step toward in-vivo bone tissue engineering and the creation of patient life-time implants. The authors have approached this challenge by utilizing combustion synthesis, to create novel materials such as NiTi + TiC as well as porous forms of materials that are commonly accepted for biomedical applications such as tricalcium phosphate and hydroxyapatite. In the SHS product, physico-chemical properties are controlled by, but not limited to, reactant stoichiometry; green density; particle size of the reactant mix; use or presence of a gasifying agent; heating rate of the reactants and gravity. By balancing these parameters, the energy of the reaction is controlled to create the desired product stoichiometry, porosity, and mechanical properties. SHS provides a means to rapidly manufacture materials, saving time and production costs as well as enabling the synthesis of custom devices through the use of individual molds. Mold materials can range from graphite to paper or paper machete. Combustion synthesis offers a method for the rapid manufacture of affordable, individual biomedical devices that will reduce patient recovery time. (C) 2006 Wiley Periodicals, Inc. J Biomed Mater Res 81A: 634-643, 2007.