Cats require more dietary phenylalanine or tyrosine for melanin deposition in hair than for maximal growth.
Cats require more dietary phenylalanine or tyrosine for melanin deposition in hair than for maximal growth.
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与最大生长相比，猫需要更多的膳食苯丙氨酸或酪氨酸来促进毛发中黑色素的沉积。
DOI：
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发表时间：
2002
期刊：
影响因子：
--
通讯作者：
J. Morris
中科院分区：
文献类型：
--
作者：
P. Anderson;Q. Rogers;J. Morris
在1986年，NRC推荐了4.0 g/kg苯丙氨酸和8.5 g/kg总芳香族氨基酸的饮食浓度为生长小猫的基础上，最大的增长率和氮平衡。给黑毛猫喂食含有以下苯丙氨酸+酪氨酸（Phe + Tyr）浓度（g/kg饲料）的纯化饲料：4 + 2、4 + 4、4 + 6、4 + 8、10 + 0、10 + 2、10 + 4、10 + 6、10 + 8、10 + 10、24 + 0，持续至少6个月。所有其他氨基酸的含量约为所需量的两倍。测定头发中的总黑色素和真黑素的氧化产物吡咯-2，3，5-三羧酸（PTCA）。血浆中酪氨酸浓度与头发中酪氨酸浓度呈显著的线性关系。毛发中的PTCA浓度与饮食中的Phe + Tyr之间的关系在约16 g/kg Phe + Tyr处具有拐点。用<16 g Phe + Tyr喂食的猫出现“红毛”。“我们证实了一些轶事报道，即猫的黑色毛发可以从黑色变成红棕色。建议芳香族氨基酸浓度>或=18 g/kg，以防止黑猫出现肉眼可见的红色毛发。膳食浓度>18 g总芳香族氨基酸/kg膳食促进毛发中更大的PTCA：总黑色素比率。我们不知道次要营养素的需求比生长的需求大得多。
In 1986, the NRC recommended a dietary concentration of 4.0 g/kg of phenylalanine and 8.5 g/kg of total aromatic amino acids for growing kittens on the basis of maximal growth rate and nitrogen balance. Black hair-coated cats were given purified diets containing the following phenylalanine + tyrosine (Phe + Tyr) concentrations (g/kg diet): 4 + 2, 4 + 4, 4 + 6, 4 + 8, 10 + 0, 10 + 2, 10 + 4, 10 + 6, 10 + 8, 10 + 10, 24 + 0 for at least 6 mo. All other amino acids were present at about twice the requirements. Total melanin and the oxidation product of eumelanin, pyrrole-2,3,5-tricarboxylic acid (PTCA) were measured in hair. There was a significant linear relationship between the concentrations of tyrosine in plasma and PTCA in hair. The relationship between PTCA concentration in hair and Phe + Tyr in the diet had a point of inflection at approximately 16 g/kg Phe + Tyr. Cats fed diets with <16 g Phe + Tyr developed "red hair." We confirmed the anecdotal reports that the black hair of cats can change from black to reddish brown. An aromatic amino acid concentration > or =18 g/kg is recommended for the prevention of visually discernible red hair in black-coated cats. Dietary concentrations >18 g total aromatic amino acids/kg diet promote a greater ratio of PTCA:total melanin in hair. We are unaware of a secondary nutrient requirement being so much greater than the requirement for growth.
区分 B16/C3 黑色素瘤的酪氨酸酶同工酶异质性。
DOI：
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发表时间：
1986
期刊：
The Journal of biological chemistry
影响因子：
--
作者：
Laskin,JD;Piccinini,LA
通讯作者：
Piccinini,LA
影响因子：
4
作者：
Andrzej SLOMINSKl;G. Moellmann;E. Kuklinska;A. Bomirski;J. Pawelek
通讯作者：
Andrzej SLOMINSKl;G. Moellmann;E. Kuklinska;A. Bomirski;J. Pawelek