PHOTON ABSORPTIOMETRIC ANALYSIS OF BONE DENSITY IN PRIMARY HYPERPARATHYROIDISM
PHOTON ABSORPTIOMETRIC ANALYSIS OF BONE DENSITY IN PRIMARY HYPERPARATHYROIDISM
复制标题
原发性甲状旁腺功能亢进症骨密度的光子吸收分析
DOI：
10.1016/s0140-6736(75)92950-5
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发表时间：
1975
期刊：
影响因子：
--
通讯作者：
R. Browne
中科院分区：
文献类型：
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作者：
C. Pak;R. Kaplan;C. Notz;Alan Stewart;Henry G. Bone;R. Browne
对13例男性和17例女性原发性甲状旁腺功能亢进症患者进行了桡骨远端1/3的骨密度测量。11名绝经后妇女中有7名的骨密度显著降低(与年龄匹配的对照组相比)。然而，在13名男性中只有2名和6名绝经前女性中只有1名下降。因此，大多数患有原发性甲状旁腺功能亢进症的绝经后女性的骨密度较低，而大多数患有这种疾病的男性和绝经前女性的骨密度正常。这一结果支持œ激素缺乏可能通过使骨骼对甲状旁腺激素的作用敏感而参与骨病的发生。
The density of bone in the distal third of the radius was measured in 13 men and 17 women with primary hyperparathyroidism. The bone density was significantly reduced (as compared to age-matched controls) in 7 of 11 postmenopausal women. However, it was reduced in only 2 of 13 men and in 1 of 6 premenopausal women. Thus, most of the postmenopausal women with primary hyperparathyroidism had low bone density, whereas most men and premenopausal women with this condition had normal bone density. The results support the conclusion that œstrogen deficiency may contribute to the development of bone disease by sensitising bone to the action of parathyroid hormone.