Osmotically active organic solutes in the renal inner medulla.
Osmotically active organic solutes in the renal inner medulla.
复制标题
肾内髓质中具有渗透活性的有机溶质。
作者：
R. Balaban;M. Burg
在过去的25年中，已经在哺乳动物肾脏的髓质中鉴定出了几种具有药理活性的哺乳动物肾脏有机溶质，但直到最近，它们的重要性才通过几种其他无关的研究路线的融合得到澄清，包括电子探针和NMR研究以及海洋生物的比较研究。本文旨在总结这些研究，并考虑可能的作用，农药活性的有机溶质。由于比较研究为这一分析提供了大量的理论框架，我们将从它们开始。
Several osmotically–active mammalian kidney organic solutes have been identified in the medulla of mammalian kidney over the past 25 years, but only recently has their significance been clarified by the convergence of several otherwise unrelated lines of investigation, including electron probe and NMR studies and comparative studies of marine organisms. The purpose of this review is to summarize those studies and to consider the likely roles of the osmotically–active organic solutes. Since the comparative studies provided much of the theoretical framework for this analysis, we will start with them.