Analysis of clinicians' attitudes towards pharmacogenomics
Analysis of clinicians' attitudes towards pharmacogenomics
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DOI：
10.2217/pme.11.43
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发表时间：
2011-09-01
影响因子：
2.3
通讯作者：
Van Riper, Marcia
中科院分区：
文献类型：
--
作者：
Dodson, Crystal;Van Riper, Marcia
目的：利用遗传信息指导患者的药物治疗将对医疗保健的临床实践产生重大影响。然而，尽管药物遗传学测试的预期好处，很少有人知道临床医生实际上是如何看待这项有前途的技术。本研究的目的是评估对药物遗传学检测的态度，这是由查佩尔山的北卡罗来纳州大学的一个跨学科研究小组进行的一项关于临床医生对药物遗传学检测的知识和态度的大型研究中以前没有强调的。材料与方法：样本包括184个开放式问题的回答。对这些答复的专题分析已经完成。结果：主题分析确定了几个主题，以前没有划定在原来的研究。分析发现了另外五个主题，包括：应用问题，缺乏成功的整合，可访问性，潜在的危害和乐观。结论：未来的研究临床医生对药物基因组学的态度评估应纳入这些主题。此外，教育活动传达有关药物基因组学的知识，需要成为随时提供给医疗保健提供者。最后，需要进行一项研究，解决与药物基因组学相关的任何差异。
Aim: The use of genetic information to guide a patient's drug therapy will have a great influence on clinical practice within healthcare. However, despite the prospective benefits of pharmacogenetic testing, little is known regarding what clinicians actually think about this promising technology. The purpose of this study was to assess attitudes towards pharmacogenetic testing not previously highlighted within a larger study on clinicians' knowledge and attitudes about pharmacogenetic testing conducted by an interdisciplinary group of researchers at the University of North Carolina at Chapel Hill. Materials & methods: The sample included 184 responses to an open-ended question. A thematic analysis of these responses was completed. Results: The thematic analysis identified several themes that were not previously delineated within the original study. The analysis uncovered five additional themes including: application concerns, lack of successful integration, accessibility, potential harm and optimism. Conclusion: Future research on the assessment of attitudes of clinicians concerning pharmacogenomics should incorporate these themes. In addition, educational activities conveying knowledge concerning pharmacogenomics needs to become readily available to healthcare providers. Finally, a study that addresses any disparity related to pharmacogenomics needs to be undertaken.