Multifocal cutaneous mucormycosis complicating polymicrobial wound infections in a tsunami survivor from Sri Lanka
Multifocal cutaneous mucormycosis complicating polymicrobial wound infections in a tsunami survivor from Sri Lanka
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DOI：
10.1016/s0140-6736(05)71046-1
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发表时间：
2005-03-05
期刊：
影响因子：
168.9
通讯作者：
Konecny, P
中科院分区：
文献类型：
--
作者：
Andresen, D;Donaldson, A;Konecny, P
一名在 2004 年 12 月 26 日海啸中受伤的男子返回悉尼治疗软组织损伤。尽管使用了广谱抗生素、外科伤口清创术和警惕的伤口护理，他的病情仍然恶化。之前清创的大腿伤口出现了肌肉和脂肪坏死，之前的擦伤也出现了坏死性病变。组织学分析显示三个不相邻部位存在毛霉菌病，并且从切除的伤口组织中分离出线状霉菌。伤口感染，包括细菌和真菌感染，无疑会增加海啸受灾地区已记录的发病率和死亡率。幸存者可能会出现皮肤毛霉菌病的其他原因，但这种疾病可能很难诊断，甚至更难治疗，特别是对于那些留在受影响地区的人。
A man injured in the tsunami of Dec 26, 2004, returned to Sydney for management of his soft-tissue injuries. Despite broad-spectrum antibiotics, surgical wound debridement, and vigilant wound care, his condition worsened. Muscle and fat necrosis developed in a previously debrided thigh wound, and necrotising lesions arose from previous abrasions. Histological analysis showed mucormycosis in three non-contiguous sites, and Apophysomyces elegans was isolated from excised wound tissue. Wound infections, both bacterial and fungal, will undoubtedly add to the morbidity and mortality already recorded in tsunami-affected areas. Other causes of cutaneous mucormycosis might develop in survivors, but this disease can be difficult to diagnose and even harder to treat, particularly in those remaining in affected regions.