Associations Between Mothers' and Their Children's Weights at 4 Years of Age.
Associations Between Mothers' and Their Children's Weights at 4 Years of Age.
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DOI：
10.1089/chi.2010.0419
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发表时间：
2010-08-01
期刊：
影响因子：
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通讯作者：
Strawderman MS
中科院分区：
文献类型：
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作者：
Olson CM;Demment MM;Carling SJ;Strawderman MS
探讨母亲体重特征作为4岁子代超重（BMI≥85百分位和<95百分位）和肥胖（BMI≥95百分位）预测因子的重要性。采用卡方分析和logistic回归分析对321对母亲产后体重保持的观察性队列研究样本进行分析。母亲妊娠早期BMI和婴儿出生体重均与4岁时后代肥胖风险增加呈正相关（p <0.05）。研究发现，在预测儿童肥胖风险方面，这两个变量之间存在显著的相互作用。这是由于肥胖妇女中肥胖儿童的比例很高，她们的婴儿出生时体重小于3公斤。妊娠期净体重增加与儿童肥胖风险无关，但与正常体重和超重妇女的婴儿出生体重呈正相关。降低超重和肥胖妇女孕前母体体重指数，防止所有妇女在怀孕期间体重过度增加，似乎是解决儿童肥胖流行病的适当策略。
To examine the importance of maternal weight characteristics as predictors of overweight (BMI ≥85th percentile and <95th percentile) and obesity (BMI ≥ 95th percentile) in offspring at age 4 years. Chi-square and logistic regression analyses were conducted on a sample of 321 mother/child pairs from an earlier observational cohort study on mothers’ postpartum weight retention. Maternal early pregnancy BMI and infant birth weight were each positively and significantly (p <0.05) associated with increased risk of obesity in offspring at age 4 years. A significant interaction was found between these two variables in predicting children’s risk of obesity. It was driven by the high proportion of obese children among obese women who had infants weighing < 3 kg at birth. Net gestational weight gain was not associated with obesity risk in children, but was positively associated with infant birth weight among normal weight and overweight women. Reducing maternal BMI in the preconception period among overweight and obese women and preventing excessive weight gain in pregnancy for all women appear to be appropriate strategies to address the childhood obesity epidemic.