Exploring the Role of Staphylococcus aureus in Inflammatory Diseases.
Exploring the Role of Staphylococcus aureus in Inflammatory Diseases.
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探索金黄色葡萄球菌在炎症性疾病中的作用
DOI：
10.3390/toxins14070464
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发表时间：
2022-07-06
期刊：
影响因子：
4.2
通讯作者：
Liu, Xueting
中科院分区：
文献类型：
--
作者：
Chen, Huanquan;Zhang, Junyan;He, Ying;Lv, Zhuoyi;Liang, Zhengtong;Chen, Jianze;Li, Peishan;Liu, Jiawei;Yang, Hongchen;Tao, Ailin;Liu, Xueting
Staphylococcus aureus is a very common Gram-positive bacterium, and S. aureus infections play an extremely important role in a variety of diseases. This paper describes the types of virulence factors involved, the inflammatory cells activated, the process of host cell death, and the associated diseases caused by S. aureus. S. aureus can secrete a variety of enterotoxins and other toxins to trigger inflammatory responses and activate inflammatory cells, such as keratinocytes, helper T cells, innate lymphoid cells, macrophages, dendritic cells, mast cells, neutrophils, eosinophils, and basophils. Activated inflammatory cells can express various cytokines and induce an inflammatory response. S. aureus can also induce host cell death through pyroptosis, apoptosis, necroptosis, autophagy, etc. This article discusses S. aureus and MRSA (methicillin-resistant S. aureus) in atopic dermatitis, psoriasis, pulmonary cystic fibrosis, allergic asthma, food poisoning, sarcoidosis, multiple sclerosis, and osteomyelitis. Summarizing the pathogenic mechanism of Staphylococcus aureus provides a basis for the targeted treatment of Staphylococcus aureus infection.
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DOI：
10.1084/jem.178.1.337
发表时间：
1993-07-01
期刊：
The Journal of experimental medicine
影响因子：
--
作者：
Suttorp N;Fuhrmann M;Tannert-Otto S;Grimminger F;Bhadki S
通讯作者：
Bhadki S
影响因子：
6.5
作者：
Amagai, M;Yamaguchi, T;Stanley, JR
通讯作者：
Stanley, JR
影响因子：
24.3
作者：
Bachert, Claus;Humbert, Marc;Broeker, Barbara M.
通讯作者：
Broeker, Barbara M.
银屑病皮损中的肽聚糖和肽聚糖特异性 ThI 细胞
影响因子：
7.3
作者：
Baker, B. S.;Laman, J. D.;Fry, L.
通讯作者：
Fry, L.
影响因子：
3.1
作者：
BHAKDI, S;MUHLY, M;HUGO, F
通讯作者：
HUGO, F