Constant Flow Inflation of the Lungs

Constant Flow Inflation of the Lungs
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肺部恒流充气

DOI:
10.1111/j.1399-6576.1966.tb01014.x
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发表时间:
1966
影响因子:
2.1
通讯作者:
Duncan A. Holadav
Duncan A. Holadav
中科院分区:
医学4区
文献类型:
--
作者:
C. Rattenborg;Duncan A. Holadav

文献摘要

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在恒流充气期间从上呼吸道获得的压力曲线可以分析呼吸器官的机械特性。恒流技术已被发现适用于人工通气力学的理论分析(RATTENBORG (1956)6 和 MAPLESON (1959)4)、肺灌注减少对肺力学影响的研究(GERST、RATENBORG、HOLADAY (1959)z 和 SEVERINGHAUS、SWENSON、FINLEY、LATEGOLA、WILLIAMS (1961)8)以及呼吸器官粘弹性特性的应力松弛(HUGHES, MAY, WIDDICOMBE (1959y 和 DON, ROBSON (1966)')。该技术还用于通过分别通气每个肺来研究单侧变化(SEVERINGHAUS, SWENSON, FINLEY, LAGEGOLA, WILLIAMS (196 1)8)或同时通气(RATENBORG, BENFIELD, NIGRO,GAGO,ADAMS(1962)')通过支气管分隔器,我们将考虑(1)弹性和(2)非弹性阻力和(3)呼吸器官的粘弹性特性对上气道压力反应的影响。肺部的隔室具有不同的时间常数,导致肺部空气分布不均匀或空气滞留。
The pressure curve obtained from the upper airways during constant flow inflation allows for an analysis of the mechanical properties of the respiratory organs. The constant flow technique has been found suitable for theoretical analysis of mechanics of artificial ventilation (RATTENBORG ( 1956)6 and MAPLESON ( 1959)4), in studies of effects on pulmonary mechanics of reduced pulmonary perfusion (GERST, RATTENBORG, HOLADAY ( 1959)z and SEVERINGHAUS, SWENSON, FINLEY, LATEGOLA, WILLIAMS (1961)8) and in the studies of the stress relaxation of the visco-elastic properties of the respiratory organs (HUGHES, MAY, WIDDICOMBE (1959y and DON, ROBSON (1966)'). The technique has also been used to study unilateral changes by ventilating each lung separately (SEVERINGHAUS, SWENSON, FINLEY, LAGEGOLA, WILLIAMS ( 196 1)8) or both simultaneously ( RATTENBORG, BENFIELD, NIGRO, GAGO, ADAMS ( 1962) ') through a bronchial divider. We will consider the effects on the upper airway pressure response to square flow inflation of (1) elastic and of (2) the non-elastic resistance and ( 3 ) uiscoelastic properties of the respiratory organs. We will include the following conditions: (1) ventilation of normal symmetrical lungs, (2) the effect of increased airway resistance, causing increased functional residual capacity and (3) ventilation of lungs with compartments having different time constants, causing uneven distribution of air in the lungs, or air trapping.