Seasonal variability of the correlation network of antibiotics, antibiotic resistance determinants, and bacteria in a wastewater treatment plant and receiving water
Seasonal variability of the correlation network of antibiotics, antibiotic resistance determinants, and bacteria in a wastewater treatment plant and receiving water
复制标题
废水处理厂和受纳水中抗生素、抗生素耐药性决定因素和细菌相关网络的季节性变化
DOI：
10.1016/j.jenvman.2022.115362
复制
发表时间：
2022
期刊：
影响因子：
--
通讯作者：
Ran Liu
中科院分区：
文献类型：
--
作者：
Weitao Shen;Yu Chen;Ning Wang;Ping Wan;Zhenyan Peng;Huajin Zhao;Wei Wang;Lilin Xiong;Shenghu Zhang;Ran Liu
污水处理厂是环境沃茨中抗生素、抗生素耐药性决定因素和细菌的重要来源。但目前还不清楚它们是否能在废水和环境沃茨中保持相对稳定的关系。分析了夏季污水处理厂对上述3种污染物的去除能力及其对环境沃茨的影响，并在前期研究的基础上，探讨了夏季和冬季污水中3种污染物与环境沃茨的关系。结果表明，夏季细菌去除能力较差，出水氟喹诺酮类药物浓度高于进水，处理后intI1、tetW、qnrB和ermB的丰度增加。变形菌门和拟杆菌门是构成细菌间关联网络的主要细菌，在夏、冬两季稳定存在。然而，氟喹诺酮类药物在夏季和冬季的抗生素和抗生素耐药性决定簇网络中占据重要地位。冬季抗生素与耐药决定因素的相关性较低。有趣的是，细菌、抗生素和抗生素耐药决定因素之间的关系在夏季主要是正相关，在冬季主要是负相关。本研究分析了废水和环境沃茨中稳定存在的细菌、抗生素和抗生素耐药决定簇之间的关系，为后续针对性季节性控制废水和环境沃茨中的新型污染物指明了方向。
Sewage treatment plants are an essential source of antibiotics, antibiotic resistance determinants, and bacteria in environmental waters. However, it is still unclear whether they can maintain a relatively stable relationship in wastewater and environmental waters. This study analyzed the removal capacity of the above three pollutants in the sewage treatment plant in summer and their impact on environmental waters, and then examines the relationship between the three contaminants in the wastewater and environmental waters in summer and winter based on our previous study. The results found that the removal capacity of bacteria in summer was poor, the concentration of fluoroquinolone in the effluent was higher than that in influent, and the abundance of intI1, tetW, qnrB, and ermB increased after wastewater treatment. Proteobacteria and Bacteroides were the main bacteria that constitute the correlation network between bacteria, and they existed stably in summer and winter. However, fluoroquinolones occupied a significant position in the determinant network of antibiotics and antibiotic resistance in summer and winter. There are fewer correlation between antibiotics and antibiotics resistance determinants in winter. Interestingly, the relationship between bacteria, antibiotics, and antibiotic resistance determinants was a mainly positive correlation in summer and negative correlation in winter. This study analyzed the relationship between bacteria, antibiotics, and antibiotic resistance determinants that were stable in the wastewater and environmental waters and pointed out the direction for subsequent targeted seasonal control of novel pollutants in wastewater and environmental waters.