Synchronization of the Flow and Pressure Waves Obtained With Non-Simultaneous Multipoint Measurements.
Synchronization of the Flow and Pressure Waves Obtained With Non-Simultaneous Multipoint Measurements.
复制标题
通过非同时多点测量获得的流量和压力波的同步。
DOI：
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发表时间：
2016
影响因子：
1.5
通讯作者：
K. Miyaji
中科院分区：
文献类型：
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作者：
S. Goto;Masanori Nakamura;K. Itatani;S. Miyazaki;N. Oka;T. Honda;T. Kitamura;T. Horai;M. Ishii;K. Miyaji
使用测量数据作为边界条件，使血流动力学模拟更具患者特异性。然而，在临床实践中，在多个位置同步采集数据通常是困难的。本研究提出了一种方法，用于将测量数据作为使用频率分析的流动模拟的边界条件，并讨论了最佳的截止频率，用于区分心脏和呼吸的血流动力学数据的变化，在循环。为了证明该方法的实用性，使用了Fontan循环，这是单心室生理学的最终姑息结果。结果表明，它是最佳的，以设置一个截止频率，给出了一个局部最小值的功率谱，略低于峰值频率的心跳。此外，总能量损失取决于截止频率，尽管总体流动模式似乎相似。该方法适用于Fontan循环以外的心血管系统，其中需要在不同位置获得具有多因素波动的血流动力学数据，但无法同时进行测量。
The use of measured data as boundary conditions renders hemodynamic simulations more patient-specific. However, synchronized acquisition of data at multiple locations is often difficult in clinical practice. This study proposes a method for resynchronizing measured data for use as boundary conditions for flow simulations using frequency analyses, and discusses the optimal cut-off frequency for differentiating cardiac and respiratory variation in hemodynamic data during resynchronization. To demonstrate the utility of the method, a Fontan circulation, which is the final palliative result with single-ventricle physiology, was used. The results suggest that it is optimal to set a cut-off frequency that gives a local minimum in the power spectrum that is slightly lower than the peak frequency of the heartbeat. Additionally, the total energy loss depended on the cut-off frequency, although the overall flow patterns appeared to be similar. The method is applicable to cardiovascular systems other than the Fontan circulation, where hemodynamic data with multifactorial fluctuations are required at various locations but simultaneous measurements are not possible.