Design of a high-sensor count fibre optic manometry catheter for in-vivo colonic diagnostics
Design of a high-sensor count fibre optic manometry catheter for in-vivo colonic diagnostics
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DOI：
10.1364/oe.17.022423
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发表时间：
2009-12-07
期刊：
影响因子：
3.8
通讯作者：
Dinning, Phil G.
中科院分区：
文献类型：
--
作者：
Arkwright, John W.;Underhill, Ian D.;Dinning, Phil G.
介绍了一种基于光纤布拉格光栅的人体结肠体内诊断测压导管的设计。该设计基于一种最初用于食道的设备，但在这种情况下，需要更长的传感长度和更大的灵活性，以便于结肠镜检查设备的放置，并允许进入这个复杂器官的卷曲区域。所采用的导管设计允许增加传感区域的数量，以覆盖结肠的延伸长度，同时保持高灵活性和紧密的轴向间距，以准确记录蠕动的相关特征。已经组装了72个轴向间隔为1cm的传感区域的导管，并在体内用于记录人类结肠在24小时内的蠕动收缩。压力传感器的紧密轴向间距首次确定了结肠中顺行（朝向肛门）和逆行（远离肛门）方向传播序列的复杂性。讨论了在较宽的传感器间距下错过传播序列的可能性，并提出了对传感器轴向间距较近的需求。(C) 2009年美国光学学会
The design of a fibre Bragg grating based manometry catheter for in-vivo diagnostics in the human colon is presented. The design is based on a device initially developed for use in the oesophagus, but in this instance, longer sensing lengths and increased flexibility were required to facilitate colonoscopic placement of the device and to allow access to the convoluted regions of this complex organ. The catheter design adopted allows the number of sensing regions to be increased to cover extended lengths of the colon whilst maintaining high flexibility and the close axial spacing necessary to accurately record pertinent features of peristalsis. Catheters with 72 sensing regions with an axial spacing of 1 cm have been assembled and used in-vivo to record peristaltic contractions in the human colon over a 24hr period. The close axial spacing of the pressure sensors has, for the first time, identified the complex nature of propagating sequences in both antegrade (towards the anus) and retrograde (away from the anus) directions in the colon. The potential to miss propagating sequences at wider sensor spacings is discussed and the resultant need for close axial spacing of sensors is proposed. (C) 2009 Optical Society of America