Sex Prevalence of Pediatric Kidney Stone Disease in the United States: An Epidemiologic Investigation
Sex Prevalence of Pediatric Kidney Stone Disease in the United States: An Epidemiologic Investigation
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DOI：
10.1016/j.urology.2008.12.079
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发表时间：
2009-07-01
期刊：
影响因子：
2.1
通讯作者：
Matiaga, Brian R.
中科院分区：
文献类型：
--
作者：
Novak, Thomas E.;Lakshmanan, Yegappan;Matiaga, Brian R.
目的了解诊断为上尿路结石的儿童住院出院患者的性别患病率。方法：本研究使用医疗成本和利用项目儿童住院患者数据库，对2003年儿科尿石症住院患者进行调查。我们使用国际疾病分类，第9版，临床修改代码，确定主要诊断为肾（592.0）或输尿管（592.1）结石的患者。评估了性别患病率，并将结果按年龄组分层。结果在2003年儿童住院患者数据库中，结石形成的儿童患者的性别分布随年龄的变化有显著差异。在第一个十年中，男性优势被发现在第二个十年中已经转变为女性优势。然而，总的来说，在儿科人群中，女孩比男孩更容易受到结石的影响。结论：在这个具有全国代表性的样本中，儿童尿石症的性别分布随着年龄的变化而变化，男孩在第一个十年更常见，女孩在第二个十年更常见。虽然这一独特的流行病学发现的原因尚不清楚，但其他研究可以建立在这一假设生成工作的基础上。中华泌尿外科杂志（英文版），2009。(C) 2009爱思唯尔公司
OBJECTIVES To define the sex prevalence of inpatient hospital discharges for pediatric patients diagnosed with upper urinary tract stone disease.METHODS The study examined inpatient admissions for pediatric urolithiasis in 2003, using the Healthcare Cost and Utilization Project Kids' Inpatient Database. We used the International Classification of Disease, 9th edition, Clinical Modification codes, to identify patients with a principal diagnosis of renal (592.0) or ureteral (592.1) calculi. Sex prevalence was assessed, and the results were stratified by age group.RESULTS In the 2003 Kids' Inpatient Database, the sex distribution among pediatric patients with stone formation varied significantly by age. In the first decade of age, a male predominance was found that had shifted to a female predominance in the second decade. Overall, however, girls in the pediatric population were more commonly affected by stones than were boys.CONCLUSIONS In this nationally representative sample, the sex distribution of pediatric urolithiasis varied with age, with boys more commonly affected in the first decade of age and girls in the second decade. Although the reason for this unique epidemiologic finding is not readily apparent, additional studies can build on this hypothesis-generating work. UROLOGY 74: 104-108, 2009. (C) 2009 Elsevier Inc.