SERIAL RECONSTRUCTION OF THE CHARACTERISTIC GRANULE OF THE LANGERHANS CELL
SERIAL RECONSTRUCTION OF THE CHARACTERISTIC GRANULE OF THE LANGERHANS CELL
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朗格汉斯细胞特征颗粒的连续重建
DOI：
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发表时间：
1968
影响因子：
7.8
通讯作者：
Thomas H. Reed
中科院分区：
文献类型：
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作者：
R. Sagebiel;Thomas H. Reed
在电镜下分析人表皮连续切片后，制作了同一朗格汉斯细胞中单个颗粒的三维模型。这些模型表明，颗粒是由一个扁平或弯曲的正交的颗粒网，其外部由一个限制膜，这可能是盘形，杯形，或两种形状的组合。这种形状的多样性解释了在单个电子显微镜照片中看到的颗粒的许多构型。通常，颗粒在一个边缘处或附近具有泡状部分。这种颗粒的三维结构证明了以前使用的描述性术语的不准确性，这种颗粒应该被简单地称为“朗格汉斯细胞颗粒”。"
Three-dimensional models of individual granules in the same Langerhans cell were made after analyzing serial sections of human epidermis in the electron microscope. These models revealed that the granule is made up of a flattened or curved orthogonal net of particles which is bounded externally by a limiting membrane and which may be disc-shaped, cup-shaped, or combinations of both shapes. This variety of shapes accounts for the many configurations of the granule seen in individual electron micrographs. Usually, the granule has a vesicular portion at, or near one margin. This demonstration of the three-dimensional structure of the granule establishes the inaccuracy of previously used descriptive terms, the granule should be called simply the "Langerhans cell granule."