Restoring Finger-Specific Sensory Feedback for Transradial Amputees via Non-Invasive Evoked Tactile Sensation.
Restoring Finger-Specific Sensory Feedback for Transradial Amputees via Non-Invasive Evoked Tactile Sensation.
复制标题
DOI：
10.1109/ojemb.2020.2981566
复制
发表时间：
2020
影响因子：
5.8
通讯作者：
Lan N
中科院分区：
文献类型：
--
作者：
Hao M;Chou CH;Zhang J;Yang F;Cao C;Yin P;Liang W;Niu CM;Lan N
目的：本研究评估了用电刺激诱发触觉（ETS）恢复经桡动脉截肢者手指特异性感觉反馈的可行性。方法：在这里，我们研究了初级体感皮层（SI）的ETS使用脑磁图反应。结果：SI激活揭示了因果关系与周围刺激的残肢皮肤上的手指区域。峰潜伏期与从外周到SI的神经传递有关。SI反应的峰值强度与外周刺激的强度成正比，表明从皮肤受体到SI神经元有一条直接的神经通路。切断侧SI的活动区与侏儒的指/手图一致，与对侧手的活动区形成镜像。通过感觉反馈，截肢者可以识别假肢手指上的压力，就像在失去的手指上一样。结论：结果证实，从外周到SI的直接神经通路可以有效地将手指特异性感觉信息传递给这些截肢者。
Objective: This study assessed the feasibility to restore finger-specific sensory feedback in transradial amputees with electrical stimulation of evoked tactile sensation (ETS). Methods: Here we investigated primary somatosensory cortical (SI) responses of ETS using Magnetoencephalography. Results: SI activations revealed a causal correlation with peripheral stimulation of projected finger regions on the stump skin. Peak latency was accountable to neural transmission from periphery to SI. Peak intensity of SI response was proportional to the strength of peripheral stimulation, manifesting a direct neural pathway from skin receptors to SI neurons. Active regions in SI at the amputated side were consistent to the finger/hand map of homunculus, forming a mirror imaging to that of the contralateral hand. With sensory feedback, amputees can recognize a pressure at prosthetic fingers as that at the homonymous lost fingers. Conclusions: Results confirmed that the direct neural pathway from periphery to SI allows effective communication of finger-specific sensory information to these amputees.