Chronic gastrointestinal symptoms and quality of life in the Korean population
Chronic gastrointestinal symptoms and quality of life in the Korean population
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DOI：
10.3748/wjg.14.6388
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发表时间：
2008-11-07
影响因子：
4.3
通讯作者：
Chung, In-Sik
中科院分区：
文献类型：
--
作者：
Jeong, Leong-Jo;Choi, Myung-Gyu;Chung, In-Sik
目的：评估韩国人群慢性胃肠道症状的患病率及其对健康相关生活质量（HRQOL）的影响。方法：横断面调查，使用可靠和有效的罗马II基于问卷，对随机选择的居民进行，年龄在18至69岁之间。所有受访者都在家中或办公室接受了一组采访者的采访。慢性胃肠道症状对HRQOL的影响采用韩国版36项一般健康问卷（SF-36）进行评估。结果：在1807名符合条件的受试者中，调查了1417名（78.4%：男性762名，女性655名）。在受访者中，18.6%表现出至少一种慢性胃肠道症状。胃食管反流病（GERD）的患病率为3.5% (95% CI, 2.6-4.5)，定义为每周至少发生一次胃灼热和/或胃酸反流。根据Rome U标准，未调查的消化不良、肠易激综合征（IBS）和慢性便秘患病率分别为11.7% （95% CI, 10.1-13.5）、2.2% （95% CI, 1.5-3.1）和2.6% （95% CI, 1.8-3.5）。与没有慢性胃肠道症状的受试者（n = 1153）相比，患有GERD （n = 50）、未调查的消化不良（n = 166）和肠易激综合征（n = 31）的受试者在SF-36量表的大多数域上的得分明显较差。结论：韩国人群中GERD、未调查消化不良和IBS的患病率分别为3.5%、11.7%和2.2%。在该社区中，与健康相关的生活质量在患有胃食管反流、未调查的消化不良和肠易激综合征的受试者中显著受损。(C) 2008 WJG出版社。版权所有。
AIM: To evaluate the prevalence of chronic gastrointestinal symptoms and their impact on health-related quality of life (HRQOL) in the Korean population.METHODS: A cross-sectional survey, using a reliable and valid Rome II based questionnaire, was performed on randomly selected residents, between 18 and 69 years in age. All respondents were interviewed at their homes or offices by a team of interviewers. The impact of chronic gastrointestinal symptoms on HRQOL was assessed using the Korean version of the 36-item Short-Form general health survey (SF-36).RESULTS: Of the 1807 eligible subjects, 1417 (78.4%: male 762; female 655) were surveyed. Out of the respondents, 18.6% exhibited at least one chronic gastrointestinal symptom. The prevalence of gastroesophageal reflux disease (GERD), defined as heartburn and/or acid regurgitation experienced at least weekly, was 3.5% (95% CI, 2.6-4.5). The prevalence of uninvestigated dyspepsia, irritable bowel syndrome (IBS) and chronic constipation based on Rome U criteria were 11.7% (95% CI, 10.1-13.5), 2.2% (95% CI, 1.5-3.1), and 2.6% (95% CI, 1.8-3.5) respectively. Compared with subjects without chronic gastrointestinal symptoms (n = 1153), those with GERD (n 50), uninvestigated dyspepsia (n = 166) and IBS (n = 31) had significantly worse scores on most domains of the SF-36 scales.CONCLUSION: The prevalence of GERD, uninvestigated dyspepsia and IBS were 3.5%, 11.7% and 2.2% respectively, in the Korean population. The health-related quality of life was significantly impaired in subjects with GERD, uninvestigated dyspepsia and IBS in this community. (C) 2008 The WJG Press. All rights reserved.