The traditional Chinese medicine Qiangjing tablet prevents blood‐testis barrier injury induced by CdCl2 through the PI3K/Akt/Rictor signaling pathway

The traditional Chinese medicine Qiangjing tablet prevents blood‐testis barrier injury induced by CdCl2 through the PI3K/Akt/Rictor signaling pathway
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DOI:
10.1002/tox.23706
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发表时间:
2022-11
影响因子:
4.5
通讯作者:
Yifeng Shen;Yao-Dong You;Kun Zhu;Guangsen Li;Xiaopeng Huang;Di'Ang Chen;Fang Yang;Liang Dong
Yifeng Shen;Yao-Dong You;Kun Zhu;Guangsen Li;Xiaopeng Huang;Di'Ang Chen;Fang Yang;Liang Dong
中科院分区:
医学3区
文献类型:
--
作者:
Yifeng Shen;Yao-Dong You;Kun Zhu;Guangsen Li;Xiaopeng Huang;Di'Ang Chen;Fang Yang;Liang Dong

文献摘要

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镉(Cd)等环境污染物可能对精子产生有害影响,并通过破坏血睾屏障(BTB)降低男性生育能力。因此,研究了中药强精片(QJP)对镉诱导的小鼠精子质量和睾丸BTB改变的影响。
Environmental contaminants such as cadmium (Cd) may have a deleterious impact on sperm and reduce male fertility by compromising the blood‐testis barrier (BTB). Hence, the effects of the traditional Chinese medicine Qiangjing tablet (QJP) on sperm quality and BTB alterations induced by Cd in mouse testes were examined.