Evaluation of serum and pleural levels of soluble B7-H4 in lung cancer patients with pleural effusion

Evaluation of serum and pleural levels of soluble B7-H4 in lung cancer patients with pleural effusion
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DOI:
10.3109/1354750x.2015.1068858
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发表时间:
2015-01-01
期刊:
影响因子:
2.6
通讯作者:
Wang, Qingbo
Wang, Qingbo
中科院分区:
医学4区
文献类型:
--
作者:
Xu, Chunhua;Qian, Lihua;Wang, Qingbo

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方法:采用ELISA法检测90例肺癌恶性胸腔积液和58例良性胸腔积液患者血清中SB7-H4和CEA水平。结果:肺癌组胸腔积液、血清中SB7-H4和CEA水平及其比值(F/S)均显著高于良性胸腔积液组(P
Objective: To evaluate the diagnostic value of sB7-H4 and CEA in both serum and pleural effusion of lung cancer patients.Methods: Levels of sB7-H4 and CEA in 90 patients with malignant pleural effusion due to lung cancer and 58 patients with benign pleural effusion were measured by ELISA.Results: The sB7-H4 and CEA levels in pleural effusion, serum and their ratio (F/S) were higher in lung cancer group than that in benign group (p