Association Between Optimism and Serum Antioxidants in the Mid life in the United States Study
Association Between Optimism and Serum Antioxidants in the Mid life in the United States Study
复制标题
DOI：
10.1097/psy.0b013e31827c08a9
复制
发表时间：
2013-01-01
影响因子：
3.3
通讯作者：
Kubzansky, Laura D.
中科院分区：
文献类型：
--
作者：
Boehm, Julia K.;Williams, David R.;Kubzansky, Laura D.
目的：心理和身体健康通常被概念化为没有疾病；很少有研究涉及积极的心理和身体功能。例如，乐观与降低疾病风险和生物功能障碍有关，但很少有研究评估与健康生物功能标记物的相关性。因此，我们调查了积极健康的两个指标之间的联系：乐观和血清抗氧化剂。方法：对982名来自美国中年研究的男性和女性的乐观情绪和抗氧化剂浓度之间的横截面关联进行了评估。主要测量包括自我报告的乐观情绪(用修订后的生活定向测试进行评估)和九种不同抗氧化剂(类胡萝卜素和维生素E)的血清浓度。回归分析评估了根据人口统计学、健康状况和健康行为调整的模型中乐观情绪和抗氧化剂浓度之间的关系。结果：在年龄调整的模型中，乐观情绪的标准差每增加一个标准差，类胡萝卜素浓度就增加3%到13%。对人口统计特征和健康状况的控制减弱了这种联系。水果和蔬菜的消费以及吸烟状况被认为是乐观情绪和血清类胡萝卜素之间潜在联系的潜在途径。乐观情绪与维生素E没有显著关联。结论：乐观情绪与较高的类胡萝卜素浓度相关，这种关联部分可以用饮食和吸烟状况来解释。影响的方向不能最终确定。考虑到乐观主义者可能从事与更多血清抗氧化剂相关的健康行为，以及更多血清抗氧化剂可能与更好的身体健康相关，从而增强乐观情绪，这种影响可能是双向的。
Objective: Psychological and physical health are often conceptualized as the absence of disease; there is less research that addresses positive psychological and physical functioning. For example, optimism has been linked with reduced disease risk and biological dysfunction, but very little research has evaluated associations with markers of healthy biological functioning. Thus, we investigated the association between two indicators of positive health: optimism and serum antioxidants. Methods: The cross-sectional association between optimism and antioxidant concentrations was evaluated in 982 men and women from the Mid life in the United States study. Primary measures included self-reported optimism (assessed with the revised Life Orientation Test) and serum concentrations of nine different antioxidants (carotenoids and vitamin E). Regression analyses evaluated the relationship between optimism and antioxidant concentrations in models adjusted for demographics, health status, and health behaviors. Results: For every standard deviation increase in optimism, carotenoid concentrations increased by 3% to 13% in age-adjusted models. Controlling for demographic characteristics and health status attenuated this association. Fruit and vegetable consumption and smoking status were identified as potential pathways underlying the association between optimism and serum carotenoids. Optimism was not significantly associated with vitamin E. Conclusions: Optimism was associated with greater carotenoid concentrations, and this association was partially explained by diet and smoking status. The direction of effects cannot be conclusively determined. Effects may be bidirectional given that optimists are likely to engage in health behaviors associated with more serum antioxidants, and more serum antioxidants are likely associated with better physical health that enhances optimism.