Pax 6 - mastering eye morphogenesis and eye evolution

Pax 6 - mastering eye morphogenesis and eye evolution
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DOI:
10.1016/s0168-9525(99)01776-x
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发表时间:
1999-09-01
期刊:
影响因子:
11.4
通讯作者:
Ikeo, K
Ikeo, K
中科院分区:
生物学1区
文献类型:
--
作者:
Gehring, WJ;Ikeo, K

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来自不同动物门的Pax 6基因均能诱导眼的异位发育,表明Pax 6基因是眼形态发生的主控基因。有人提出,后生动物中发现的各种眼睛类型是通过一种称为插入进化的机制从一个共同的原型衍生而来的。
Pax 6 genes from various animal phyla are capable of inducing ectopic eye development, indicating that Pax 6 is a master control gene for eye morphogenesis. It is proposed that the various eye-types found in metazoa are derived from a common prototype, monophyletically, by a mechanism called intercalary evolution.