Diffusion in polyelectrolyte hydrogels: Application of an obstruction-scaling model to solute diffusion in calcium alginate
Diffusion in polyelectrolyte hydrogels: Application of an obstruction-scaling model to solute diffusion in calcium alginate
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DOI：
10.1021/ma001450e
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发表时间：
2001-02-27
期刊：
影响因子：
5.5
通讯作者：
Amsden, B
中科院分区：
文献类型：
--
作者：
Amsden, B
本文提出了溶质分子在凝胶内扩散的阻塞尺度模型。考虑两种释放介质条件：低离子强度和高离子强度。该模型进行了测试，对实验数据的蛋白质扩散海藻酸钙水凝胶。该模型提供了非常好的协议的实验结果，成功地预测聚合物浓度，释放介质离子强度，和聚合物链的灵活性的影响。
An obstruction-scaling model of the diffusion of solute molecules within polyelectrolyte gels is presented. Two release medium conditions are considered: low ionic strength and high ionic strength. The model is tested against experimental data of protein diffusion in calcium alginate hydrogels. The model provides very good agreement to the experimental results, successfully predicting the effects of polymer concentration, release medium ionic strength, and polymer chain flexibility.