Association between hypertension and hearing impairment in health check-ups among Japanese workers: a cross-sectional study
Association between hypertension and hearing impairment in health check-ups among Japanese workers: a cross-sectional study
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DOI：
10.1136/bmjopen-2018-028392
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发表时间：
2019-06-01
期刊：
影响因子：
2.9
通讯作者：
Kobashi，Gen
中科院分区：
文献类型：
--
作者：
Umesawa，Mitsumasa;Sairenchi，Toshimi;Kobashi，Gen
目的预防听力损害（HI）是很重要的，因为听力恢复通常是困难的。流行病学研究已经检查了HI的危险因素。然而，高血压和HI之间的关系尚不清楚。本研究旨在明确高血压与HI之间的关系。设计横断面研究。以日本某信息通信技术公司的员工为研究对象，在该公司的24823名员工中，招募了13475名参与者，他们在年度健康检查中接受了听力测试，并且没有关于身体测量、血液测试结果和饮酒/吸烟状况的缺失数据主要结果在两个频率（1 kHz，4kHz）下进行听力测试。我们将参与者无法对1 kHz下的30 dB和/或4 kHz下的40 dB做出反应定义为总体中度HI。我们还将1或4 kHz的中度HI定义为1或4 kHz的异常发现。我们将高血压定义为收缩压≥140 mm Hg和/或舒张压≥90 mm Hg和/或服用高血压药物。调整年龄，性别，体重指数，吸烟/饮酒状况，糖尿病，高血压和HI之间的关联，我们研究了中度HI确定在980名参与者（7.3%）。其中，441例受试者（3.3%）在1 kHz下表现出中度HI，787例受试者（5.8%）在4 kHz下表现出中度HI。高血压受试者的HI患病率更高。总体中度HI，中度HI在1 kHz和中度HI在4 kHz的患病率高血压患者分别为8.7%，4.3%和6.8%，而那些没有高血压的受试者分别为6.9%，3.0%和5.6%（p<0.01，p<0.01和p=0.01，分别）。
ObjectivesPrevention of hearing impairment (HI) is important because recovery of hearing is typically difficult. Epidemiological studies have examined the risk factors for HI. However, the association between hypertension and HI remains unclear. We aimed to clarify the association between hypertension and HI.DesignCross-sectional study.SettingJapanese workers in an information and communication technologies company.ParticipantsOf 24 823 employees of the same company, we recruited 13 475 participants who underwent hearing testing by audiometry in annual health check-ups and did not have missing data regarding body measurement, blood test results and drinking/smoking status (mean age: 49.4 years; males: 86.4%).Primary outcomesHearing tests were performed at two frequencies (1 kHz, 4 kHz). We defined the inability of participants to respond to 30 dB at 1 kHz and/or 40 dB at 4 kHz as overall moderate HI. We also defined moderate HI at 1 or 4 kHz as an abnormal finding at 1 or 4 kHz. We defined hypertension as ≥140 mm Hg systolic blood pressure and/or ≥90 mm Hg diastolic blood pressure and/or taking medication for hypertension. We examined the association between hypertension and HI after adjusting for age, sex, body mass index, smoking/drinking status, diabetes mellitus, hyperlipidaemia and proteinuria.ResultsModerate HI was identified in 980 participants (7.3%). Of these, 441 participants (3.3%) exhibited moderate HI at 1 kHz, and 787 participants (5.8%) exhibited moderate HI at 4 kHz. Subjects with hypertension showed a higher prevalence of any HI. The prevalence of overall moderate HI, moderate HI at 1 kHz and moderate HI at 4 kHz among subjects with hypertension was 8.7%, 4.3% and 6.8%, while those among subjects without hypertension was 6.9%, 3.0% and 5.6% (p<0.01, p<0.01 and p=0.01, respectively).ConclusionsHypertension was associated with moderate HI in Japanese workers.