Genetic analysis of natural populations of Drosophila melanogaster in Japan. I. Protein polymorphism, lethal gene, sterility gene, inversion polymorphism and linkage disequilibrium.
Genetic analysis of natural populations of Drosophila melanogaster in Japan. I. Protein polymorphism, lethal gene, sterility gene, inversion polymorphism and linkage disequilibrium.
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日本果蝇自然种群的遗传分析。
DOI：
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发表时间：
1984
期刊：
影响因子：
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通讯作者：
Yasubumi Matsuo
中科院分区：
文献类型：
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作者：
T. Yamazaki;Y. Matsuo;Yasuhisa Inouei;Yasubumi Matsuo
同时对从黑腹果蝇2个自然群体中提取的780条第二和第三染色体进行了等位酶多态性、致死频率、不育频率、倒位频率和连锁不平衡等遗传参数的检测。得到以下结果。 1) 16个等位酶位点的平均杂合度在Akayu (AK)群体中为0.159，在Tanushimaru (TS)群体中为0.181。群体之间几乎没有观察到遗传差异（I = 0.99）。等位酶基因座之间没有观察到连锁不平衡。 2)赤汤群体和田主丸群体中In(2L)t多态性倒转频率分别为0.188和0.106。 In(2R)NS 的值为 0.115 和 0.049。 In(3L)P的值为0.009和0.037，In(3R)P的值为0.107和0.052。倒转之间不存在显着的连锁不平衡。 3)赤汤群体和田主丸群体中携带第二染色体致死率分别为0.315和0.182。第三条染色体上的频率为 0.327 和 0.305。赤鱼不育第二染色体的频率，雄性和雌性分别为0.147和0.127，第三染色体的频率分别为0.093和0.084。 Tanushimaru 种群的相应值分别为 0.091 和 0.07、0.0 和 0.084。在同一染色体的雄性和雌性不育之间发现了显着的统计关联，表明多效性基因作用。 4)倒位与等位酶之间以及倒位之间存在负或排斥连锁不平衡。没有发现具有少数优势的频率依赖选择的证据。
Genetic parameters such as allozyme polymorphisms, lethal frequency, sterility frequency, inversion frequency and linkage disequilibrium were examined simultaneously in 780 second and third chromosomes, extracted from 2 natural populations of Drosophila melanogaster. The following results were obtained. 1) The average heterozygosities of 16 allozyme loci were 0.159 in the Akayu (AK) population and 0.181 in the Tanushimaru (TS) population. Little genetic differentiation was observed between populations (I=0.99). No linkage disequilibrium was observed between allozyme loci. 2) The frequency of the polymorphic inversion In(2L)t was 0.188 and 0.106 in the Akayu and Tanushimaru populations. That of the In(2R)NS was 0.115 and 0.049. That of the In(3L)P was 0.009 and 0.037, and that of the In(3R)P was 0.107 and 0.052. There were no significant linkage disequilibria between inversions. 3) The frequency of lethal carrying second chromosomes was 0.315 and 0.182 in the Akayu and Tanushimaru populations. Those on the third chromosome were found at a frequency of 0.327 and 0.305. The frequencies of sterile second chromosomes in Akayu were 0.147 and 0.127 in males and females, and of the third chromosomes, the respective frequencies were 0.093 and 0.084. Corresponding values for the Tanushimaru population were 0.091 and 0.07, and 0.0 and 0.084, respectively. Significant statistical associations were found between male and female sterility of the same shromosome, indicating pleiotropic gene action. 4) Negative or repulsion linkage disequilibria were found between inversions and allozymes, and between inversions. No evidence of frequency dependent selection with minority advantage was found.