Respiratory Virus Infections of the Stem Cell Transplant Recipient and the Hematologic Malignancy Patient
Respiratory Virus Infections of the Stem Cell Transplant Recipient and the Hematologic Malignancy Patient
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DOI：
10.1016/j.idc.2019.02.004
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发表时间：
2019-06-01
影响因子：
4.4
通讯作者：
Strasfeld, Lynne
中科院分区：
文献类型：
--
作者：
Fontana, Lauren;Strasfeld, Lynne
血液干细胞移植受者和血液恶性肿瘤患者的呼吸道病毒感染越来越被认为是一个重要的发病率和死亡率的原因。经常重叠的临床表现使得分子诊断策略对快速诊断和了解每种呼吸道病毒不断变化的流行病学至关重要。虽然对流感有有效的抗病毒治疗，但大多数呼吸道病毒感染可通过支持性治疗加以控制。主要重点仍应放在一级预防感染控制程序和隔离预防措施、避免患病接触以及流感疫苗接种上。
Respiratory virus infections in hematologic stem cell transplant recipients and patients with hematologic malignancies are increasingly recognized as a cause of significant morbidity and mortality. The often overlapping clinical presentation makes molecular diagnostic strategies imperative for rapid diagnosis and to inform understanding of the changing epidemiology of each of the respiratory viruses. Most respiratory virus infections are managed with supportive therapy, although there is effective antiviral therapy for influenza. The primary focus should remain on primary prevention infection control procedures and isolation precautions, avoidance of ill contacts, and vaccination for influenza.