RNAmmer: consistent and rapid annotation of ribosomal RNA genes.
RNAmmer: consistent and rapid annotation of ribosomal RNA genes.
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DOI:
10.1093/nar/gkm160
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发表时间:
2007
影响因子:
14.9
通讯作者:
Ussery DW
中科院分区:
文献类型:
--
作者:
Lagesen K;Hallin P;Rødland EA;Staerfeldt HH;Rognes T;Ussery DW
The publication of a complete genome sequence is usually accompanied by annotations of its genes. In contrast to protein coding genes, genes for ribosomal RNA (rRNA) are often poorly or inconsistently annotated. This makes comparative studies based on rRNA genes difficult. We have therefore created computational predictors for the major rRNA species from all kingdoms of life and compiled them into a program called RNAmmer. The program uses hidden Markov models trained on data from the 5S ribosomal RNA database and the European ribosomal RNA database project. A pre-screening step makes the method fast with little loss of sensitivity, enabling the analysis of a complete bacterial genome in less than a minute. Results from running RNAmmer on a large set of genomes indicate that the location of rRNAs can be predicted with a very high level of accuracy. Novel, unannotated rRNAs are also predicted in many genomes. The software as well as the genome analysis results are available at the CBS web server.
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影响因子:
56.9
作者:
Venter, JC;Remington, K;Smith, HO
通讯作者:
Smith, HO
影响因子:
7
作者:
Freyhult, Eva K.;Bollback, Jonathan P.;Gardner, Paul P.
通讯作者:
Gardner, Paul P.
DOI:
10.1073/pnas.85.8.2444
发表时间:
1988-04-01
影响因子:
11.1
作者:
PEARSON, WR;LIPMAN, DJ
通讯作者:
LIPMAN, DJ
影响因子:
64.5
作者:
Schluenzen, F;Tocilj, A;Yonath, A
通讯作者:
Yonath, A
影响因子:
3.9
作者:
SRIVASTAVA, AK;SCHLESSINGER, D
通讯作者:
SCHLESSINGER, D