Nanoparticle Superlattices through Template-Encoded DNA Dendrimers
Nanoparticle Superlattices through Template-Encoded DNA Dendrimers
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DOI：
10.1021/jacs.1c07858
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发表时间：
2021-10-11
影响因子：
15
通讯作者：
Mirkin, Chad A.
中科院分区：
文献类型：
--
作者：
Cheng, Ho Fung;Distler, Max E.;Mirkin, Chad A.
导致分层结构出现的化学相互作用通常是高度复杂和难以编程的。本文报道了基于30种不同结构可重构DNA树状大分子的一系列超晶格的合成，每一种树状大分子表面都有明确数量的单链寡核苷酸（即粘端）。这些构建块与互补的dna功能化金纳米颗粒（aunp）组装在一起，产生五种不同的晶体结构，这取决于树状大分子的选择和相对称性。这些DNA树状大分子可以结合形成胶束-树状大分子，结合的程度可以根据表面活性剂的浓度和树状大分子的长度进行调节，从而产生低对称性的ti5ga4型相，这在胶体晶体工程领域尚未报道。总的来说，胶体晶体具有三种不同类型的粒子键相互作用。模板-树突，树突-树突和dna修饰的aunp -树突。，说明如何序列定义的识别和动态关联可以结合，以产生复杂的层次材料。
The chemical interactions that lead to the emergence of hierarchical structures are often highly complex and difficult to program. Herein, the synthesis of a series of superlattices based upon 30 different structurally reconfigurable DNA dendrimers is reported, each of which presents a well-defined number of single-stranded oligonucleotides (i.e., sticky ends) on its surface. Such building blocks assemble with complementary DNA-functionalized gold nanoparticles (AuNPs) to yield five distinct crystal structures, depending upon choice of dendrimer and defined by phase symmetry. These DNA dendrimers can associate to form micelle-dendrimers, whereby the extent of association can be modulated based upon surfactant concentration and dendrimer length to produce a low-symmetry Ti5Ga4-type phase that has yet to be reported in the field of colloidal crystal engineering. Taken together, colloidal crystals that feature three different types of particle bonding interactions.template-dendron, dendrimer-dendrimer, and DNA-modified AuNP-dendrimer.are reported, illustrating how sequence-defined recognition and dynamic association can be combined to yield complex hierarchical materials.