Improved growth of preterm infants receiving mother's own raw milk compared with pasteurized donor milk

Improved growth of preterm infants receiving mother's own raw milk compared with pasteurized donor milk
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DOI:
10.1111/j.1651-2227.2011.02389.x
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发表时间:
2011-12-01
期刊:
影响因子:
3.8
通讯作者:
Casper, C.
Casper, C.
中科院分区:
医学4区
文献类型:
--
作者:
Montjaux-Regis, N.;Cristini, C.;Casper, C.

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目的:确定早产儿的生长发育、喂养耐受性和感染事件是否与母亲自己的生奶(母乳)和混合巴氏杀菌母乳(供乳)的摄入量有关。方法:对2003年至2005年图卢兹儿童医院新生儿重症监护室收治的55例胎龄小于32周的早产儿进行前瞻性观察。结果:平均孕周28.6周(SD 1.5),平均出生体重1105 g(SD 282)。在纯母乳喂养期间,体重增加(g/kg/d)与母乳摄入量相关(p=0.0048,r=0.40)。坏死性小肠结肠炎与母乳量呈负相关。母乳量对早产儿感染事件无影响。结论:在早产儿中,与供体母乳相比,母亲自己的生奶可以改善体重增加。应该寻求帮助母亲增加产奶量的哺乳策略。
Aim: To determine whether growth, feeding tolerance and infectious events of preterm infants is related to the proportion of intake of mother's own raw milk (maternal milk) versus pooled pasteurized banked breast milk (donor milk).Methods: This is a prospective observational study of 55 premature infants born less than 32 weeks of gestational age admitted to the neonatal intensive care unit at the Children's Hospital of Toulouse during two 6-month periods from 2003 to 2005. Enrolled infants were exclusively on enteral feeds with maternal milk +/- donor milk.Results: Mean gestational age was 28.6 weeks (SD 1.5) and mean birth weight 1105 grams (SD 282). During the time of exclusively breast milk feeds, weight gain (g/kg/day) was correlated to the proportion of maternal milk consumed (p = 0.0048, r = 0.4). Necrotizing enterocolitis was inversely correlated to the amount of maternal milk. The amount of maternal milk did not impact on infectious events.Conclusion: Mother's own raw milk improves weight gain compared with donor milk in preterm infants. Lactation strategies should be sought that helps mothers to increase their milk production.