ENCEPHALOPATHY - AN UNCOMMON MANIFESTATION OF WORKPLACE ARSENIC POISONING
ENCEPHALOPATHY - AN UNCOMMON MANIFESTATION OF WORKPLACE ARSENIC POISONING
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DOI：
10.1002/ajim.4700150102
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发表时间：
1989-01-01
影响因子：
3.5
通讯作者：
CARON, GA
中科院分区：
文献类型：
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作者：
MORTON, WE;CARON, GA
本报告描述了两例慢性脑病与职业接触砷烟雾从热压浸渍木材。这两例均在职业性接触砷烟雾后14-18个月出现认知障碍症状。尿液中砷含量升高提供了实验室证实。一名患者因明显的精神原因住院。一个病例的神经心理测试显示除了心理症状外，新学习、近期记忆和注意力的典型和相对轻微的损伤。在停止接触和尿砷排泄恢复到正常水平后，这两例患者的症状都消失了。在未来对接触砷的工人的研究中，应该使用神经行为测试电池寻找轻度认知功能损害的记录。
This report describes two cases of chronic encephalopathy associated with occupational exposure to arsenic fumes from hot pressurized impregnation of wood. Both cases displayed symptoms of cognitive impairment with onset 14-18 months after start of occupational exposure to arsenic fumes. Laboratory confirmation was provided by elevated urine arsenic levels. One patient was hospitalized for apparent psychiatric reasons. Neuropsychologic testing of one case showed typical and relatively mild impairments of new learning, recent memory, and concentration in addition to the psychological symptoms. Symptoms in both cases disappeared following cessation of exposure and return of urine arsenic excretion to normal levels. In future studies of workers exposed to arsenic, documentation of mild impairment of cognitive function should be sought using neurobehavioral test batteries.