Fertility- and menopause-related information needs of younger women with a diagnosis of early breast cancer
Fertility- and menopause-related information needs of younger women with a diagnosis of early breast cancer
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DOI：
10.1200/jco.2005.07.773
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发表时间：
2005-08-01
影响因子：
45.3
通讯作者：
Friedlander, ML
中科院分区：
文献类型：
--
作者：
Thewes, B;Meiser, B;Friedlander, ML
目的：在绝经前妇女的治疗中使用化疗和内分泌疗法会带来生殖和妇科方面的影响，年轻妇女可能会感到痛苦，并与生育计划不一致。本多中心研究的目的是调查生育和绝经相关的信息需求与诊断的年轻女性早期breastcancer.Patients和方法228名妇女诊断为早期乳腺癌的年龄在40岁或以下的诊断和诊断后6至60个月进入试验。参与者完成了邮寄的自我报告问卷，其中包括一个专门设计的生育和更年期相关的信息需求调查和标准化措施的困扰，焦虑，生活质量，更年期症状，和信息seeking styles.Results百分之七十一的参与者讨论生育相关的问题与健康专业人士的一部分，他们的乳腺癌治疗，和86%的讨论更年期相关的问题。咨询生育或更年期专家是获得这些信息的最佳方法。在诊断时（P <0.001）和治疗决策时（P = 0.058），接受生育相关信息比接受绝经相关信息更重要。在辅助治疗期间（P <0.05）、辅助治疗信息来源完成时（P <0.001）和随访期间（P <0.001），接受绝经相关信息被认为比接受生育相关信息更重要。常见的问题，相关的感知importance were identified.Conclusion本研究的结果表明，年轻女性有未满足的需求生育和绝经相关的信息，并提供初步的经验数据，以指导更好的生育和绝经相关的患者教育材料的年轻女性诊断为早期乳腺癌的发展。
Purpose The use of chemotherapy and endocrine therapies in the treatment of premenopausal women carries with it reproductive and gynecologic implications that young women may find distressing and discordant with plans for childbearing. This multicenter study aimed to investigate fertility- and menopause-related information needs among young women with a diagnosis of early-stage breast cancer.Patients and Methods Two hundred twenty-eight women with a diagnosis of early-stage breast cancer who were aged 40 years or younger at diagnosis and who were 6 to 60 months after diagnosis were entered onto the trial. Participants completed a mailed self-report questionnaire that included a purposely designed fertility- and menopause-related information needs survey and standardized measures of distress, anxiety, quality of life, menopausal symptoms, and information-seeking style.Results Seventy-one percent of participants discussed fertility-related issues with a health professional as part of their breast cancer treatment, and 86% discussed menopause-related Issues. Consultation with a fertility or menopause specialist was the most preferred method of obtaining this information. Receiving fertility-related information was rated as being significantly more important than receiving menopause-related information at time of diagnosis (P < .001) and at treatment decision making (P = .058). Receiving menopause-related information was rated as being significantly more important than receiving fertility-related information during adjuvant treatment (P < .05), at completion of adjuvant treatment sources of information, and (P < .001) and during follow-up (P < .001). Common questions,, correlates of perceived importance were identified.Conclusion The results of this study suggest that younger women have unmet needs for fertility- and menopause-related information and provide preliminary empirical data to guide the development of better fertility- and menopause-related patient education materials for younger women with a diagnosis of early breast cancer.