Redox-Neutral Ni-Catalyzed sp3C-H Alkylation ofα-Olefins withUnactivated Alkyl Bromides
Redox-Neutral Ni-Catalyzed sp3C-H Alkylation ofα-Olefins withUnactivated Alkyl Bromides
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DOI：
10.1021/acscatal.2c01057
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发表时间：
2022-04-01
期刊：
影响因子：
12.9
通讯作者：
Martin, Ruben
中科院分区：
文献类型：
--
作者：
Buendia, Mikkel B.;Higginson, Bradley;Martin, Ruben
本文描述了未活化的烯烃与具有β-氢的烷基溴的光诱导氧化还原中性Ni-催化的sp3 C-H烷基化。该方法的特点是其简单，广泛的范围，和精致的区域和化学选择性概况，从而提供了一个切入点，伪造sp3-sp3架构。
A light-induced redox-neutral Ni-catalyzed sp3C-H alkylation of unactivated alkenes with alkyl bromides possessing beta-hydrogens is described herein. The method is distinguished by itssimplicity, wide scope, and exquisite regio- and chemoselectivityprofile, thus offering an entry point to forge sp3-sp3architectures.