Conception to Birth: Epidemiology of Prenatal Development
Conception to Birth: Epidemiology of Prenatal Development
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受孕到出生：产前发育的流行病学
DOI：
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发表时间：
1989
期刊：
影响因子：
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通讯作者：
M. Susser
中科院分区：
文献类型：
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作者：
J. Kline;Z. Stein;M. Susser
这本书的意图是阐明在流行病学的关键光下，现有的和不断发展的产前发展知识，通过所有妊娠从概念到出生。这本书分为5个部分：1)发育障碍：权衡环境原因的证据2)受孕和妊娠早期3)妊娠后期4)年龄和胎次5)物理环境繁殖和监视。第一节指导读者评估观察到的可疑致畸物与发育结果之间的关联。作者讨论了一些既定的标准，通过这些标准可以判断因果推理的质量——时间顺序、强度、一致性、特异性和连贯性。在奠定了这个基础之后，第二和第三部分绘制了流行病学发展地图。第二部分用三个连续的章节来阐述概念和损失的概率对频率测量的解释和观察到的实际频率。另外3章致力于流产数据，其中正常和异常核型已被区分。第三部分为胎儿生长及其持续时间、早产以及胎儿生长和出生体重的现有概念。第4节探讨了生殖结果分析中的两个主要问题产妇年龄和妊娠。第5节讨论了发现和控制对生殖的环境危害的公共卫生挑战，包括对监测的系统分析处理和开展监测的理由。
The intent of this book is to illuminate under the critical light of epidemiology the existing and evolving knowledge of prenatal development through all of gestation from conception to birth. The book is divided into 5 sections: 1) disorders of development: weighing the evidence for environmental causes 2) conception and early gestation 3) later gestation 4) age and parity and 5) the physical environment reproduction and surveillance. The 1st section guides readers in evaluating observed associations between suspected teratogens and developmental outcomes. The authors discuss a number of established criteria by which the quality of causal inferences might be judged--time order strength consistency specificity and coherence. After laying this groundwork the 2nd and 3rd sections draw an epidemiological map of development. The 2nd section devotes 3 consecutive chapters to the probabilities of conception and of loss to the interpretation of frequency measures and to actual frequencies observed. Another 3 chapters are devoted to miscarriage data in which normal and aberrant karyotypes have been differentiated. The 3rd section turns to fetal growth and its duration preterm delivery and existing concepts of fetal growth and birth weight. Section 4 explores 2 major issues in the analysis of reproductive outcomes maternal age and gravidity. Section 5 takes up the public health challenge of detecting and controlling environmental hazards to reproduction including a systematic analytic treatment of surveillance and the rationale for undertaking surveillance.