Computed tomography studies of lung ventilation and perfusion.
Computed tomography studies of lung ventilation and perfusion.
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DOI：
10.1513/pats.200509-099ds
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发表时间：
2005-01-01
期刊：
影响因子：
--
通讯作者：
Chon, Deokiee
中科院分区：
文献类型：
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作者：
Hoffman, Eric A;Chon, Deokiee
随着多排计算机层析成像(CT)的出现，现在可以通过使用单一成像模式来同时成像结构和功能。屏气螺旋CT提供了呼吸道和血管树的细节，以及反映肺实质状态的纹理。使用稳定的氙气洗入和/或洗出方法，使用CT扫描仪的轴向模式，通过选通到呼吸周期来获取图像，提供区域通风的详细图像，各向同性体素尺寸目前约为0.4 mm。屏气期间的轴位扫描和快速注射碘化造影剂期间的心电图门控提供了详细的区域肺血流灌注图像。这些用于研究局部肺功能的动态CT方法将在研究肺功能异质性的其他方法的背景下进行讨论。
With the emergence of multidetector-row computed tomography (CT) it is now possible to image both structure and function via use of a single imaging modality. Breath-hold spiral CT provides detail of the airway and vascular trees along with texture reflective of the state of the lung parenchyma. Use of stable xenon gas wash-in and/or wash-out methods using an axial mode of the CT scanner whereby images are acquired through gating to the respiratory cycle provide detailed images of regional ventilation with isotropic voxel dimensions now on the order of 0.4 mm. Axial scanning during a breath hold and gating to the electrocardiogram during the passage of a sharp bolus injection of iodinated contrast agent provide detailed images of regional pulmonary perfusion. These dynamic CT methods for the study of regional lung function are discussed in the context of other methods that have been used to study heterogeneity of lung function.