Relation between cardiovascular risk factors and nonrheumatic severe calcific aortic stenosis among patients with a three-cuspid aortic valve
Relation between cardiovascular risk factors and nonrheumatic severe calcific aortic stenosis among patients with a three-cuspid aortic valve
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DOI：
10.1016/s0002-9149(02)03010-2
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发表时间：
2003-01-01
影响因子：
2.8
通讯作者：
Tribouilloy, CM
中科院分区：
文献类型：
--
作者：
Peltier, M;Trojette, F;Tribouilloy, CM
这项大型前瞻性研究，控制年龄和性别，旨在检查非风湿性严重钙化主动脉瓣狭窄与心血管危险因素之间的具体关系。结果显示，全身高血压、高胆固醇血症、吸烟和肥胖与由钙化变性引起的严重主动脉狭窄存在密切关联，而与冠状动脉疾病的存在无关。
This large prospective study, controlled for age and gender, was designed to examine the specific relation between the presence of nonrheumatic severe calcific aortic stenosis and cardiovascular risk factors. The results show a strong association of systemic hypertension, hypercholesterolemia, smoking, and obesity with the presence of severe aortic stenosis due to calcific degeneration, independently of the presence of coronary artery disease.