Can visual information encoded in cortical columns be decoded from magnetoencephalography data in humans?
Can visual information encoded in cortical columns be decoded from magnetoencephalography data in humans?
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DOI：
10.1016/j.neuroimage.2015.07.011
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发表时间：
2015-11-01
期刊：
影响因子：
5.7
通讯作者：
Pantazis, Dimitrios
中科院分区：
文献类型：
--
作者：
Cichy, Radoslaw Martin;Ramirez, Fernando Mario;Pantazis, Dimitrios
这是一个主要的开放问题，是否在人类的非侵入性成像方法可以解码的信息编码在空间尺度一样精细的基本功能单位的皮层：皮质柱。我们在五个脑磁图（MEG）实验中通过研究柱级编码的视觉功能：对比度边缘方向来解决这个问题。我们发现，MEG信号包含方向特定的信息，早在刺激开始后约50毫秒，即使控制混淆，如过度表示特定的方向，刺激边缘的相互作用，和全球形式相关的信号。理论模型证实了这一经验结果的合理性。我们的研究结果的一个重要后果是，在人类大脑中编码的信息在皮层列的水平，一般应访问的电生理信号的多变量分析。(C)2015爱思唯尔公司All rights reserved.
It is a principal open question whether noninvasive imaging methods in humans can decode information encoded at a spatial scale as fine as the basic functional unit of cortex: cortical columns. We addressed this question in five magnetoencephalography (MEG) experiments by investigating a columnar-level encoded visual feature: contrast edge orientation. We found that MEG signals contained orientation-specific information as early as approximately 50 ms after stimulus onset even when controlling for confounds, such as overrepresentation of particular orientations, stimulus edge interactions, and global form-related signals. Theoretical modeling confirmed the plausibility of this empirical result. An essential consequence of our results is that information encoded in the human brain at the level of cortical columns should in general be accessible by multivariate analysis of electrophysiological signals. (C) 2015 Elsevier Inc. All rights reserved.