Comparative Evaluation of the Nanosphere Verigene RV plus Assay and the Simplexa Flu A/B & RSV Kit for Detection of Influenza and Respiratory Syncytial Viruses
Comparative Evaluation of the Nanosphere Verigene RV plus Assay and the Simplexa Flu A/B & RSV Kit for Detection of Influenza and Respiratory Syncytial Viruses
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DOI：
10.1128/jcm.02504-12
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发表时间：
2013-01-01
影响因子：
9.4
通讯作者：
Miller, Melissa B.
中科院分区：
文献类型：
--
作者：
Alby, Kevin;Popowitch, Elena B.;Miller, Melissa B.
我们使用200例回溯性鼻咽标本和150例前瞻性鼻咽标本，对纳米微球Verigene RV+和Simplexa Flu A/B及RSV试验进行了评估。RV+对甲型流感病毒的敏感性和特异性分别为96.6%和100%，对乙型流感病毒的敏感性和特异性分别为100%和99.7%，对呼吸道合胞病毒的敏感性和特异性分别为100%和100%，而Simplexa试验的敏感性和特异性分别为82.8%和99.7%，76.2%和100%，94.6%和100%。
Using retrospective (n = 200) and prospective (n = 150) nasopharyngeal specimens, we evaluated the Nanosphere Verigene RV+ and the Focus Diagnostics Simplexa Flu A/B & RSV tests. Overall, RV+ demonstrated sensitivities and specificities of 96.6% and 100% for influenza A virus, 100% and 99.7% for influenza B virus, and 100% and 100% for respiratory syncytial virus (RSV), while the Simplexa test sensitivities and specificities were 82.8 and 99.7%, 76.2 and 100%, and 94.6 and 100%, respectively.