Serological investigation of the prevalence of anti-dengue IgM and IgG antibodies in Attapeu Province, South Laos
Serological investigation of the prevalence of anti-dengue IgM and IgG antibodies in Attapeu Province, South Laos
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DOI：
10.1111/j.1198-743x.2003.00854.x
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发表时间：
2004-02-01
影响因子：
14.2
通讯作者：
Jelinek, T
中科院分区：
文献类型：
--
作者：
Peyerl-Hoffmann, G;Schwöbel, B;Jelinek, T
在2001年8月至10月的雨季期间，在老挝南部的Attapeu地区采集了225份主要是发热患者的血液样本，确定了登革热抗体的流行情况。一个IgM捕获ELISA是阳性的（0.4%）样品，而177（79%）样品是阳性的间接IgG ELISA。在IgG阳性标本中，20份（11.3%）血片也呈恶性疟原虫阳性。登革热似乎在这一地区很普遍，但临床登革热诊断仍然很困难，特别是在疾病的最初几天，医生必须区分登革热和其他发热性疾病。
The prevalence of dengue antibodies was determined in the Attapeu region of South Laos with 225 blood samples collected from mostly febrile patients during the rainy season August - October 2001. An IgM capture ELISA was positive for one (0.4%) sample, while 177 (79%) samples were positive in an indirect IgG ELISA. Of the positive IgG samples, 20 (11.3%) were also positive on blood slides for Plasmodium falciparum. Dengue fever seems to be widespread in this area, but clinical dengue diagnosis remains difficult, especially in the first days of illness when physicians have to discriminate between dengue and other febrile illnesses.