Properties of long alkyl-chained resorcin[4]arenes in bilayers and on the Langmuir trough
Properties of long alkyl-chained resorcin[4]arenes in bilayers and on the Langmuir trough
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DOI：
10.1039/c2nj40337d
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发表时间：
2013
影响因子：
3.3
通讯作者：
Priyanka Ogirala;S. Negin;C. Agena;C. Schäfer;T. Geisler;J. Mattay;G. Gokel
中科院分区：
文献类型：
--
作者：
Priyanka Ogirala;S. Negin;C. Agena;C. Schäfer;T. Geisler;J. Mattay;G. Gokel
用平面双层膜电导电压钳装置和朗缪尔槽研究了两种含10-癸硫基癸基侧链的间苯二酚芳烃和一种空穴配体。前者检测磷脂双层中孔形成的存在，后者探测两亲物作为单层的聚集行为。这些两亲物的Langmuir槽行为表明，较高的极性头基团占主导地位的组织，但随着头基团极性降低，单层组织是由四个侧链占主导地位。在这三者中，即，间苯二酚芳烃、八甲基间苯二酚芳烃和空穴配体中，只有甲基化的头基衍生物在双层中形成离子传导孔。
Two resorcinarenes and one cavitand having 10-(decylthio)decyl side chains were studied by using both a planar bilayer conductance voltage clamp device and a Langmuir trough. The former detects the presence of pore formation in a phospholipid bilayer and the latter probes the aggregation behavior of the amphiphiles as a monolayer. The Langmuir trough behavior of these amphiphiles showed that higher polarity head groups dominated organization, but as the head group polarity decreased, monolayer organization was dominated by the four side chains. Among the three, i.e., resorcinarene, octamethyl resorcinarene, and cavitand, only the methylated head group derivative formed ion-conducting pores in bilayers.